宇宙長期滞在模擬の生理的変化を人工重力の遠心負荷で予防出来るか

对日本大学医学院10名健康男生进行了为期4天的6度俯卧床休息（HDT）实验。由清水公司提供，在他们的空间开发实验室设置了一个1.8米半径的人体离心机，上述HDT设备附在离心机室旁边。10名受试者在严格控制下，每天除15分钟的分泌和1小时的2Gz+离心外，保持HDT 24小时。从目前的许多HDT研究来看，很明显，在4天HDT的许多生理变化中，只有红细胞压积显著增加。在4天的HDT期间，平均血细胞比容值没有明显增加。Convertino等人进行的4天HDT中，在床上走动或站立2小时（lG负荷模拟）等其他对策无法拦截红细胞压积的增加。本报告是短臂离心机的第一个数据，证明离心比其他对策更有效地抑制正常在地面HDT 4天引起的红细胞压积增加。考虑到这些因素，在长期的空间生活中，相对于其他应对措施，如一些运动或其他常规方法，离心机是防止空间微重力条件下生理变化的首选。

4 days 6 degrees head down tilt bed rest (HDT) experiments were conducted for 10 healthy male students at Nihon University School of Medicine. By a courtesy of Shimizu Co., a 1.8 m radius human centrifuge was set at their Space Development Laboratory and the above mentioned HDT facilitiy was atatched next to the centrifuge room. 10 subjects were kept under a severe control to keep the HDT 24 hours except 15 minutes of secretion and one hour of 2Gz+ centrifugation every day. From many HDT studies up to the present, it has been clear that only hematocrit significantly increases among many physiological changes according to 4 days HDT.No significant increase was observed among the averaged hematocrit values during the 4 days HDT.By other countermeasures as walking arround or standind on the bed (lG load simulation) for up to 2 hours in 4 days HDT, conducted by Convertino et al., hematocrit increase could not be intercepted. This report is the first deta of short arm centrifuge, proving that the centrifugation is more effective than other countermeasures to inhibit the hematocrit increase normally induced in 4 days HDT on the ground. Considering these facts, centrifugation is the first choice to be adopted for artificial gravity in a long term space life, compared with the other countermeasures such as some exercises or other conventional ways to prevent the physiological changes due to the microgravity condition in space.