Development of the spatio-temporal measurement system using real-time NMR imaging

为了开发“使用实时NMR成像的时空测量系统”，计划了三个子项目：NMR信号的快速生成、使用NMR信号的实时NMR图像重建以及开发3D NMR图像数据的显示和分析软件。在第一个项目中，我们介绍了一个梯度射频探头，它可以产生快速和强烈的磁场梯度，并开发了一个高性能的脉冲编程器的MRI使用数字信号处理器（DSP）板。因此，我们成功地在32 mm x 32 mm的视场（FOV）中以80 ms的时间间隔采集了连续的2D NMR图像。在第二个项目中，我们证明了实时图像重建和显示系统可以使用一个高性能的个人计算机与商业AD转换器板。因此，我们已经成功地重建和显示一个128 × 128像素的核磁共振图像在约50毫秒。对于第三个项目，我们已经开发了面绘制软件和体绘制软件在Microsoft Windows95实时三维核磁共振成像。利用在这些项目中获得的结果，我们构建了世界上第一个实时3D NMR成像系统。

To develop the "apatio-temporal measurement system using real-time NMR imaging", three sub-projects were planned : fast generation of NMR signal, real-time NMR image reconstruction using the NMR signal, and development of display and analysis software for 3D NMR image data. For the first project, we introduced a gradient-RF probe which can generate fast and intense magnetic field gradients and developed a high-performance pulse programr for MRI using a digital signal processor (DSP) board. As a result we succeeded to acquire successive 2D NMR images at the 80 ms time intervals in the 32 mm x 32 mm field of view (FOV). For the second project, we demonstrated that the real-time image reconstruction and display system can be built using a high performance personal computer with a commercial AD converter board. As a result, we have succeeded to reconstruct and display a 128 x 128 pixel NMR image at about 50 ms. For the third project, we have developed surface rendering software and volume rendering software on Microsoft Windows95 for real-time 3D NMR imaging. Using the results obtained in these projects, we constructed the world's first real-time 3D NMR imaging system.