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Development of system of irradiation synchronized with respiration gate

呼吸门同步照射系统的研制

基本信息

批准号：
08671044
负责人：
MORITA Kazuo
金额：
$ 0.77万
依托单位：
SAPPORO MEDICAL UNIVERSITY
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
1996
资助国家：
日本
起止时间：
1996 至 1997
项目状态：
已结题

来源：
https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-08671044/
关键词：
Respiratory movement Lung tumor Treatment planning 放射線治療

项目摘要

We examined how we can decide the appropriate irradiation field and radiation technique to the target moved by respiration. When we consider the radiation technique to the tumor of the lung apex, the target volume is usually decided by using CT imagings that are taken when breath is stopped. However, because the tumor of the lung apex moves from anterior oblique to posterior oblique at the respiration, the radiation dose of some part of the target can decrease. Then, we took CT imagings at inhalation and expiration before the treatment planning. The tumor volumes at inhalation and expiration were summed and the treatment planning was performed by using the summed target volume. By this treatment planning, we can decide the direction of the beam to prevent the target deviate from the irradiation field. To realize this, it is required to have the function to synthesize the two target volumes. We could solve that problem by inputting the two target volumes. We could solve that problem by … More inputting the two target volumes to the three-dimensional treatment planning system. Because this makes the movement of the target in the three-dimensional space make clear, we can irradiate the target through the optimal direction. In the usual way, after the treatment planning, we verify the movement of the target with the x-ray simulator and enlarge the radiation field. As compared with the usual way, this new method could decrease the treatment volume more. When the target moves with the physiological movement of the organ, there was the uncertainty at the decision of the target volume in the usual way of the treatment planning in which CT imagings at one moment of the moving target are used. Then, we developed the method of three-dimensional treatment planning by using two mamaximum values of the moving target. By using this method, we can solve the uncertainty in the usual way of the treatment planning, know the minimum treatment volume, minimize the danger that the target volume deviates from the radition field, and make the optimum treatment planning to the moving target. Less

探讨了如何对呼吸运动引起的靶区选择合适的照射野和照射技术。在肺尖肿瘤的放射治疗中，靶区的选择通常是通过呼吸停止时的CT图像来确定的。然而，由于肺尖肿瘤在呼吸时从前斜位移动到后斜位，因此靶区的某些部分的辐射剂量可以降低。然后，在治疗计划之前，我们在吸气和呼气时进行了CT成像。将吸气和呼气时的肿瘤体积相加，并使用相加的靶体积进行治疗计划。通过这种治疗计划，我们可以决定光束的方向，以防止目标偏离照射野。为了实现这一点，需要具有合成两个目标体积的功能。我们可以通过输入两个目标体积来解决这个问题。我们可以解决这个问题， ...更多信息将所述两个目标体积输入到所述三维治疗计划系统。因为这使得目标在三维空间中的运动变得清晰，我们可以通过最佳方向照射目标。在通常的方式中，在治疗计划之后，我们用X射线模拟器验证目标的移动并扩大辐射野。与通常的方法相比，这种新方法可以更多地减少治疗体积。当目标随着器官的生理运动而运动时，在使用运动目标的一个时刻的CT成像的治疗规划的通常方式中，在目标体积的决定上存在不确定性。在此基础上，提出了利用运动靶点的两个最大值进行三维治疗计划的方法。利用该方法，可以解决常规治疗计划中的不确定性问题，知道最小治疗体积，使靶区偏离辐射野的危险最小化，对运动靶区做出最优治疗计划。少