Crystallographic studies on inorganic components of black-and calcium bilirubinate gallstones

黑胆红素胆石和胆红酸钙胆石无机成分的晶体学研究

• 批准号: 08671478
• 负责人: SAITO Kazuyoshi
• 金额: $ 1.34万
• 依托单位: Iwate Medical University, School of Medicine
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 1996
• 资助国家: 日本
• 起止时间: 1996 至 1997
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-08671478/
• 关键词: black gallstone; calciumbilirubinate stone; calcium carbonate stone; aragonite; calcite; hydroxyapatite; whitlockite; calcite; ビリルビンマルシウム胆石; X線回折法; vaterite; 炭酸カルシウム結晶

Chemical and crystallographic analysis, by powder X-ray diffractometry, were carried out on black-and calcium bilirubinate gallstones.Hydroxyapatite and whitlockite [TCP] were identified in black qallstones. HAP was found in twenty gallstones speciments, TCP in eight, but the remaining six specimens contained HAP plus TCP.There was a close correlation between the calcium contents and phosphorus contents of both HAP,the following correlation was found : Y=2.154X+18.00, r=0.9943. For the specimens containing TCP,Y=1.964X+13.43, r=0.9994. The slope of each regression line was nearly equal to the idealized Ca/P weight ratio of 2.157 (HAP) or 1.941 (TCP).Crystallographic pattern of calcium carbonate in calcium carbonate pius calcium phosphate stone group, calcite was dominant, but in calcium carbonate group aragonite was dominant.On X-ray diffractometry, some peak similar with that of calcium bilirubinate stones was found at low angle area.

本文用粉末X-射线衍射法对胆囊结石进行了化学和晶体学分析，在黑色结石中鉴定出羟基磷灰石和白磷钙石。20例胆囊结石标本中检出HAP，8例检出TCP，其余6例标本中均为HAP + TCP，两者钙磷含量呈显著正相关，相关系数为Y=2.154X+18.00，r=0.9943。含TCP的试样Y=1.964X+13.43，r=0.9994。结果表明，碳酸钙+磷酸钙结石组中碳酸钙的晶体结构以方解石为主，而碳酸钙组中以文石为主，X射线衍射分析在低角区出现了一些与碳酸钙结石相似的衍射峰。

项目成果

斎藤和好ほか: "後腹膜神経鞘腫" 日本臨状・領域別症候群シリーズ. No.11. 115-117 (1997)

Kazuyoshi Saito 等：“腹膜后神经鞘瘤”日本临床和区域综合征系列第 11. 115-117 (1997)。

Kazuyoshi SAITO: "Calcifing Gallstones (in Japanese)" Nippon Rinsho. No.9. 412-414 (1996)

Kazuyoshi SAITO：“胆结石钙化（日语）”Nippon Rinsho。

斎藤 和好: "胆石症の手術----開腹下胆嚢摘出術" 外科治療. 76・5. 874-877 (1997)

Kazuyoshi Saito：“胆石症手术——开腹胆囊切除术” 76・5 (1997)。

斎藤 和好: "胆石症の手術…開腹下胆嚢摘出術" 外科治療. 76・5. 874-877 (1997)

Kazuyoshi Saito：“胆石症手术...开腹胆囊切除术” 76・5（1997）。

斎藤 和好: "消化器疾患最近の治療97′-98′(胆石症)" 南江堂(分担執筆), 418(4) (1997)

Kazuyoshi Saito：“消化系统疾病 97′-98′（胆石症）的最新治疗” Nankodo（撰稿人），418(4) (1997)