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Development of noninvasive measurement of peripheral circulation and its application for health care

Development of noninvasive measurement of peripheral circulation and its application for health care
末梢循环无创测量技术的发展及其在医疗保健中的应用
批准号:
10557044
负责人:
NAKAMURA Hideki
金额:
$2.82万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
1998
资助国家:
日本
项目状态:
已结题
起止时间:
1998 至 1999

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中文摘要
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英文摘要
Recently, it has become possible to noninvasively measure the oxygen saturation level of arterial blood, finger arterial pressure, and the elasticity of digital arteries using photosensors and light-emitting diodes(LED). Photosensors have also been used to measure the mechanical properties of digital arteries and indices such as the blood volume in peripheral tissue.There are various peripheral circulatory indices that was obtained using a laser beam and near infrared light from LED. Though these indices can be obtained noninvasively or minimally invasively by application of short-term pressure, the continuity of measurement is lost when cuff pressure is applied. Measurement is insufficient using light of only 1 wavelength in this method. Determination of an absolute value can be improved if 2 wavelengths was used.We has also carried out preliminary examination of the assessment of peripheral circulatory function using photosensors. The apparatus, the principle involved in measurement, the assessment of elasticity and nonlinear characteristics of the digital arteries, the measurement of tissue blood volume was establishied.
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Toda,M.: "Linkage-disequilibrium mapping narrows the Fukuyama-type congenital muscular dystrophy (FCMD) candidate region to <100Kb." Amer.J.Human Genet.59. 1313-1320 (1996)
Toda,M.:“连锁不平衡图谱将福山型先天性肌营养不良症 (FCMD) 候选区域缩小至 <100Kb。”
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Shinka T,et al.: "Genetic variation on the Y chromosome in the Japanese population and the implications for modern human Y chromosome lineage"Journal of Human Genetics. 44. 245-250 (1999)
Shinka T 等人:“日本人群中 Y 染色体的遗传变异及其对现代人类 Y 染色体谱系的影响”《人类遗传学杂志》。
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Nakamura,H.: "Development of noninvasive measurement of peripheral circulation and its medical application" (Environmental Health and Preventive Medicine. 2. 1-10 (1997)
Nakamura,H.:“外周循环无创测量及其医学应用的发展”(环境健康与预防医学。2. 1-10 (1997)
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Miyake,M.: "YAC and cosmid contigs emcompassing the Fukuyama-type congenital muscular dystrophy (FCMD) candidate region on 9q3l." Genomies. 40. 284-293 (1997)
Miyake,M.:“YAC 和粘粒重叠群包含 9q3l 上的福山型先天性肌营养不良症 (FCMD) 候选区域。”
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10
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