The effects of exercises and stresses on the growth of malignant cells and non-specific immune activity

我们已经通过许多动物实验和健康管理调查试图阐明生活方式与老年人生物预防功能之间的关系。由此可见，减轻应激和适当的自由跑动对小鼠非特异性免疫活性获得的生物预防反应的改善有重要作用。我们尝试了以下三个动物实验，通过测量肿瘤的重量和一些生物反应测试来评估他们的生活方式（压力、身体健康和营养）对癌症的影响。我们采用生理应激（电刺激）和心理应激作为应激负荷方法，采用跑步轮自主运动和踏板机强制运动作为锻炼方法，采用硒和螺旋藻作为抗氧化剂的补充。两种方法处理应激大鼠背部皮肤的恶性细胞重量均显著高于对照组。但令人惊讶的是。给药至恶性肿瘤细胞，应激负荷明显下降后停止应激负荷。这些结果与中性粒细胞功能、NK活性和淋巴细胞有丝分裂反应的结果一致。与对照组相比，自主运动组恶性细胞重量显著降低，NK活性显著升高，而踏板机组则无明显变化。与对照组相比，硒组和螺旋藻组的恶性细胞重量均降低。虽然在应激和运动实验中没有发现其生物预防功能发生较大变化，但螺旋藻与恶性细胞组提示了诱导部分亚群淋巴细胞的可能性

We have been tried to clarify the relation between life style and biophylaxis function by many animal experiments, the survey through health administration in elderly people yet. As these results, lesser stress and adequate free running play big role to the improvement of the their biophylaxis which was gained by non-specific immune activity. We tried following three animal experiments to evaluate the influence on the cancer of their life style (stress, physical fitness and nutrition) by the measure of the tumor's weight and some tests for the biophylaxis. We used physical stress (electric stimulation) and psychological stress as stress load methods, voluntary exercise by running wheel and compulsory exercise by tread mill as exercise methods, and selenium and spirulina as the supplements of anti-oxidants.The weight of malignant cells administered from the back skin of rats loaded stresses by two methods increased significantly in comparison with control rats. But surprisingly. those of rats which was given stresses up to the administration of malignant cells and was stopped stress load after it decreased significantly. These results was in accord with the results of neutrophilis function, NK actitivity and mitogenic response of lymphocytes. The weight of malignant cells in voluntary exercise group decreased and NK activity increased significantly in comparison with control group, but those of tread mill group did not change. The weight of malignant cells Se group and Spirulina group decreased both in comparison with control group. Though their biophylaxis function were not recognized big change such as the stress and the exercise experiments, Spirulina with malignant cells group suggested the possibility of the induction of some subsets of lymphocytes