Effect of voluntary exercise on the specific and nonspecific immunity in rats

本报告包括第一部分（自愿运动对感染大鼠生理功能的影响）和第二部分（自愿运动和跑步机运动对大鼠生理功能的影响）。第一部分：以运动组SPF Fischer大鼠为研究对象，采用单轮跑笼和对照组进行为期20周的常规运动和沙门氏菌感染条件下运动的效果观察。本研究表明：(1)运动组在摄入更多的食物和水的情况下，其体重增长速度明显低于对照组，且运动组体重与脂肪组织重量、体重与总跑步距离均存在显著的相关关系。(2)适度运动对改善血脂代谢有一定效果，对预防脂肪肝有一定的作用。(3)运动组对非特异性免疫的影响大于运动组。第二部分：将雄性Fischer大鼠分为三组：跑步机跑步组(T)、自主运动组(V)和对照组(C)，研究跑步机和自主运动对身体功能的影响。T组在跑步机上以20m/min的强度跑步30分钟。每周减少5天，持续13周。本研究结果如下：自愿运动：1)尽管食量增加，但体重增加和脂肪组织重量均显著低于C组。2)肝脏、心脏、睾丸和肾脏中多种矿物质和微量金属含量显著高于其他两组。自愿运动：1)尽管食量增加，但体增重和脂肪组织重量显著低于c组。2)肝脏和心脏中多种矿物质和微量金属含量显著低于其他两组。3)每体重心重显著高于其他两组。4)对机体免疫功能起重要作用的胸腺和脾脏重量显著低于C组。(5)流式细胞术分析两组对胸腺细胞和外周血细胞中细胞冲浪者标志物的作用差异不明显。少

This report includes part 1 (Effects of voluntary exercise on the physioloical function in the infected rats) and Part 2 (Effects of voluntary and treadmill exercise on the physiological function in rats. Part 1 : The effect of not only customary voluntary exercise, but also one under the conditions of salmonella infection was examined using SPF Fischer rats of the exercise group by individual wheel running cages and the control group for 20 weeks. The present study showed that : (1) The rates of body weight gain of the exercise group were markedly inhibited than those of the control group in spite of more consumption of food and water, and the correltion not only between body weight and adipose tissue weight, but also between body weight and total running distance were significantly were shwed in the exercise group. (2) The moderate exercise practice have the effectiveness to improvement for serum lipid metabolism and the possibility to prevention of their fatty liver. (3) The effect … More of the non-specific immunity was recognize only in exercise group. Part 2 : The effects of treadmill and voluntary exercise on physical function were exemined in male Fischer rats divided into three groups : Treadmill run-ning (T), voluntary exercise (V), and Control (C) groups. T group was imposed the treadmill running for 30 minutes in the intensity 20m/min.by 5 days in a week for 13 weeks. Follwing results were obtained in this study. Voluntary exercise : 1) Body weight gain and adipise tissue weight were significantly lowere than that of C group in spite of more consumption of food. 2) The concentration of many minerals and trace metal in liver, heart, testis and kidney were significantly higher than those of other two groups. Voluntary exercise : 1) Body weight gain and adipise tissue weight were significantly lowere than that of Cgroup in spite of more consumption of food. 2) The concentration of many mineral and trace metal in liver and heart were significantly lower than those of other two groups. 3) Heart weight per body weight was significantly higher other two groups. 4) The weight of thymus and spleen which play as important part in our immune function were significantly lower than that of C group. (5) The difference of effect to cell surfer marker in thymocytes and peripheral blood cell by flowcytometry analysis were not recognize in the both groups. Less