Synthesis and Application of New Host Molecules derived from Macrocycles.

1. 成功合成了双臂冠状啡。它们对银离子有很高的选择性。在水中以环糊精为原料，采用光环加成法制备了含氨基的冠诺芬。利用离子偶极相互作用，与冠状醚成功合成了[2]-和[3]链烷。用两种不同的方法研究了[60]富勒烯双合物的产物分布。苯法只得到顺式-1。所有外消旋物（反式-2、反式-3和顺式-3）通过手性高效液相色谱柱层析成功地分解成每个对映体。二加糖对碱金属离子具有独特的选择性。成功地合成了含有乙酸乙酯单元的杯芳烃。对碱金属离子具有良好的可萃取性。随着乙酸乙酯单元数的减少，对Rb^+、Cs^+等较大离子的可萃取性逐渐降低。它们在氨基醇的作用下成功转化为树突状分子。

1. Double armed crownophanes were successfully synthesized. They showed the high ion selectivity for silver ion. Crownophanes containing amino group were also synthesized with cyclodextrin in water by photocycloaddition. Catenanes including[2]- and [3] catenanes were successfully synthesized by using ion-dipole interaction with crownether.2. The product distribution of [60]fullerene bisadducts was investigated by the different two methods. The benzyne method exclusively gave cis-1 form. All racemates (trans-2, trans-3, and cis-3) were successfully resolved into each enantiomer by using chiral HPLC column chromatography. Bisadducts attaching crownether moiety showed the unique ion selectivity for alkali metalions.3. Calixarenes having some ethyl acetate units were successfully synthesized. They showed the good extractability for alkali metal ions. When the number of the ethylacetate unit decreased, the extractability for larger ions like Rb^+ and Cs^+ gradually decreased. They were successfully converted to dendrimer type molecules with amino alcohol.