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Study on Fluid Dynamic Characteristics of Turbulent Blood Flow

Study on Fluid Dynamic Characteristics of Turbulent Blood Flow
湍流血流的流体动力学特性研究
批准号:
11650199
负责人:
TSUKIYA Tomonori
金额:
$1.41万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
1999
资助国家:
日本
项目状态:
已结题
起止时间:
1999 至 2000

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中文摘要
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英文摘要
The pressure - flow rate relationship in the ventricular assist system consisting of an artificial heart is helpful in order to diagnose and detect abnormal condition of the system, or to develop indirect measurement system which saves sensors for pressure and flow rate of the device being used. For example, we have developed the indirect flow rate measurement system using the power consumption of the driving motor of the centrifugal blood pump. This relationship, however, is subject to the physical properties of blood as well as the configuration of the system. The physical properties of flowing blood, or rheology of blood, is essential for such aims, but reports on physical properties of flowing blood under turbulent state, which is often observed in the mechanical assisting devices like artificial hearts, has hardly been investigated. The pressure drop across the circular pipe of turbulent flow was measured and compared between goat blood and a Newtonian fluid. Goat blood demonstrat … More ed slight decrease in the pressure drop than the Newtonian fluid, and the magnitude of the decrease in pressure drop was independent of blood cell concentration. The indirect measurement of flow rate of a centrifugal blood pump using motor power consumption was attempted, in which the effect of viscosity change on the accuracy was investigated. The centrifugal blood pump developed in our research institute was installed between the left apex and the descending aorta making a left heart bypass. The flow rate measured by this method has demonstrated sufficient accuracy for practical use when the viscosity is known. The extent of errors fluctuated with the change of hematocrit after in the course of time after surgical operation. The errors could be corrected by measuring the viscosity of the blood to the practically acceptable range by calibration data obtained with Newtonian fluids. The difference in pressure drop in turbulence due to Non-Newtonian properties, which was observed in the turbulent pipe flow, was found to have negligible effects in this measurement method of flow rate for the practical use. Less
期刊论文(3)
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Tsukiya T, et al.: "Study on the Fluid Dynamic Characteristics of Turbulent Blood Flow"Proceedings of the JSME 11^<th> Bioengineering Conference. 99-03. 260-261 (1999)
Tsukiya T 等人:“湍流血流的流体动力学特性研究”JSME 第 11 届生物工程会议论文集。
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通讯作者:
築谷朋典 他5名: "血液流の流体工学的特性に関する研究"第11回バイオエンジニアリング講演会講演論文集. 99-03. 260-261 (1999)
Tomonori Tsukutani 等 5 人:“血流的流体力学特性研究”第 11 届生物工程会议记录 99-03(1999)。
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通讯作者:
Tsukiya T, et al.: "Performance of an Newly Developed Implantable Centrifugal Blood Pump"ASAIO Journal. (in press). (2001)
Tsukiya T 等人:“新开发的植入式离心血泵的性能”ASAIO 杂志。
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Development of a Blood Pump for Implantable Right Ventricular Assist Device
Evaluation of the effect of electromagnetic exposure by implantable medical device
The effect of air-blood mixture on blood trauma in extracorporeal circulation devices.
Development of the Multistage Centrifugal Blood Pump for the Extended Use of Rotary Blood Pumps
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