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Development of the Multistage Centrifugal Blood Pump for the Extended Use of Rotary Blood Pumps

多级离心式血泵的开发以扩展旋转式血泵的使用

基本信息

批准号：
18360094
负责人：
TSUKIYA Tomonori
金额：
$ 3.9万
依托单位：
National Cardiovascular Center Research Institute
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (B)
财政年份：
2006
资助国家：
日本
起止时间：
2006 至 2007
项目状态：
已结题

项目摘要

The present study deals with the development of a novel centrifugal pump which consists of the multistage impeller. The use of a multistage impeller leads to generation of high pressure without increasing the rotational speed of the motor. The direct advantage of this structure will be the decreased amount of the blood cell destruction(blood trauma) in the device.The first prototype was designed for the virtual working condition of the flow rate of 3.0 L/min and the pressure difference of 500 mmHg. The prototype employs the following design features to ensure generation of high pressure.1. the suction volute in the inlet passage2. the impeller profile for high pressure3. the double volute to minimize the radial thrust on the impellerThe first prototype demonstrated the sufficient pump performance. The CFD analysis of the internal flow field of the device has revealed the need for design improvement in terms of the blood cell destruction and thrombus formation in the device.1 addition of the front shroud to the impeller2 use of the wider gap in the tongue of the double volute casing3 use of the shrouded return vaneThe second prototype with the above improvements demonstrated a bit lower hydraulic performance due to the increase in the internal leakage flow associated with the design change to enhance the wash-out condition of the device. However, we succeeded in decreasing the maximum shear stress over the lethal value for blood cell destruction and in elimination of the stagnant area which possibly leads to the thrombus formation.

本研究涉及开发一种由多级叶轮组成的新型离心泵。使用多级叶轮可以在不增加电机转速的情况下产生高压。这种结构的直接优点是减少了装置内血细胞破坏（血液创伤）的量。第一个样机是针对流量为3.0 L/min、压差为500 mmHg的虚拟工作条件而设计的。该样机采用以下设计特点来确保高压的产生： 1．入口通道中的吸入蜗壳2。高压叶轮轮廓3。双蜗壳可最大限度地减少叶轮上的径向推力第一个原型机展示了足够的泵性能。设备内部流场的 CFD 分析表明，需要在设备中的血细胞破坏和血栓形成方面进行设计改进。1 在叶轮上添加前护罩2 在双蜗壳的舌部中使用更宽的间隙3 使用带护罩的回流叶片具有上述改进的第二个原型显示出稍低的水力性能，因为与设计更改相关的内部泄漏流量增加了。增强装置的冲洗条件。然而，我们成功地将最大剪切应力降低到血细胞破坏的致死值之上，并消除了可能导致血栓形成的停滞区域。