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Development of the Multistage Centrifugal Blood Pump for the Extended Use of Rotary Blood Pumps

多级离心式血泵的开发以扩展旋转式血泵的使用

基本信息

批准号：
18360094
负责人：
TSUKIYA Tomonori
金额：
$ 3.9万
依托单位：
National Cardiovascular Center Research Institute
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (B)
财政年份：
2006
资助国家：
日本
起止时间：
2006 至 2007
项目状态：
已结题

项目摘要

The present study deals with the development of a novel centrifugal pump which consists of the multistage impeller. The use of a multistage impeller leads to generation of high pressure without increasing the rotational speed of the motor. The direct advantage of this structure will be the decreased amount of the blood cell destruction(blood trauma) in the device.The first prototype was designed for the virtual working condition of the flow rate of 3.0 L/min and the pressure difference of 500 mmHg. The prototype employs the following design features to ensure generation of high pressure.1. the suction volute in the inlet passage2. the impeller profile for high pressure3. the double volute to minimize the radial thrust on the impellerThe first prototype demonstrated the sufficient pump performance. The CFD analysis of the internal flow field of the device has revealed the need for design improvement in terms of the blood cell destruction and thrombus formation in the device.1 addition of the front shroud to the impeller2 use of the wider gap in the tongue of the double volute casing3 use of the shrouded return vaneThe second prototype with the above improvements demonstrated a bit lower hydraulic performance due to the increase in the internal leakage flow associated with the design change to enhance the wash-out condition of the device. However, we succeeded in decreasing the maximum shear stress over the lethal value for blood cell destruction and in elimination of the stagnant area which possibly leads to the thrombus formation.

本文介绍了一种新型多级叶轮离心泵的研制。使用多级叶轮可以在不增加电机转速的情况下产生高压。这种结构的直接优点是减少了设备中血细胞的破坏(血液创伤)。第一台样机是为流量为3.0MH2O/分钟、压差为500MMHG的虚拟工作条件设计的。该样机采用了以下设计特点，以确保产生高压。进气通道2中的吸气蜗壳。高压叶轮型线3。双蜗壳将对叶轮的径向推力降至最小第一台样机展示了足够的泵性能。对装置内部流场的CFD分析表明，在装置内的血细胞破坏和血栓形成方面需要进行设计改进。1在叶轮上增加前护罩2使用双蜗壳壳体的舌部更宽的间隙3使用带冠回流叶片进行上述改进的第二个样机显示出稍低的水力性能，这是由于为改善装置的清洗条件而改变设计导致的内部泄漏流量增加。然而，我们成功地降低了血细胞破坏的致死值以上的最大剪应力，并消除了可能导致血栓形成的停滞区。