OPTIMIZATION OF A CENTRIFUGAL BLOOD PUMP FOR IMPLANTED USE
OPTIMIZATION OF A CENTRIFUGAL BLOOD PUMP FOR IMPLANTED USE
批准号:
12558117
负责人:
TSUKIYA Tomonori
金额:
$0.9万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2000
资助国家:
日本
项目状态:
已结题
起止时间:
2000 至 2001
中文摘要
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英文摘要
The purpose of this study was to optimize the design of the components of the ultracompact centrifugal blood pump which is implanted into the patient as the ventricular assist device. The pump was drastically miniaturized to the half of the former prototype by employing direct drive DC brushless motor.The impeller design was improved considering the hydrodynamic performances, electric efficiency, washing out condition on the blood-contacting surfaces, and blood cell damage impaired by the pump. The pump performance in vitro satisfied the need for left ventricular assist device. The curved configuration of the inlet duct was also evaluated for better anatomical fitting. The collective performance as a left ventricular assist device was evaluated using an adult goat in chronic animal experiments. 65 days of survival was realized using the pump installed outside the body.The signals of the driving motor was successfully utilized to estimate the flow rate of the pump with sufficient response. This method can possibly eliminate the use offlowmeter, and also be used to detect the adverse conditions, such as the sucking by excessive pump operation.
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H, Sawairi T, Konishi Y, Masuzawa T, Okada Y: "Development of an Implantable Centrifugal Blood Pump"Journal of Congestive Heart Failure and Circulatory Support. Vol.1,No.4. 305-308 (2001)
H、Sawairi T、Konishi Y、Masuzawa T、Okada Y:“植入式离心血泵的开发”充血性心力衰竭和循环支持杂志。
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Tsukiya T, Taenaka Y, Tatsumi E, Takano H: "Performance of a Newly Developed Implantable Centrifugal Blood Pump"ASAIO Journal. 47. 559-562 (2001)
Tsukiya T、Taenaka Y、Tatsumi E、Takano H:“新开发的植入式离心血泵的性能”ASAIO 杂志。
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築谷朋典 他6名: "中長期使用のための小型・高効率補助人工心臓システムの開発と製品化"電気学会研究会資料. LD-00-56. 11-14 (2000)
Tomonori Tsukutani 等 6 人:“用于中长期使用的紧凑且高效的心室辅助系统的开发和商业化” LD-00-56 (2000)。
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Tsukiya T, Taenaka Y, Tatsumi E, Takano H, et al.: "Application of Indirect Flow Rate Measurement Using Motor Driving Signals to a Centrifugal Blood Pump with an Integrated Motor"Artificial Organs. Vol.25,No.9. 692-696 (2001)
Tsukiya T、Taenaka Y、Tatsumi E、Takano H 等人:“使用电机驱动信号进行间接流量测量在带有集成电机的离心血泵中的应用”人工器官。
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築谷朋典 他5名: "遠心ポンプを用いた体内埋込型補助人工心臓システムの開発"第13回バイオエンジニアリング講演会講演論文集. 00-35. 136-137 (2001)
Tomonori Tsukutani 等 5 人:“使用离心泵开发植入式辅助人工心脏系统”第 13 届生物工程会议记录 00-35 (2001)。
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海外基金