Development of method of decision making of reconstructing intercostal artery during thoracic aortic operation
Development of method of decision making of reconstructing intercostal artery during thoracic aortic operation
批准号:
11671301
负责人:
WATANABE Takao
金额:
$2.11万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
1999
资助国家:
日本
项目状态:
已结题
起止时间:
1999 至 2000
中文摘要
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英文摘要
Paraplegia after thoracoabdominal aortic operation is very miserable complication. We must decide which intercostal artery must be reconstructed or not. But the decision making is very drfficutt. So we studied the possibility of prediction of intercostal arteries must be reconstructed.Method: Neuron exciting aminooacid was infused to intercostal arteries by using two balloon catheters inserted from femoral artery. The evoked potential of spinal cord during infusion was measured.Results: The change of evoked potential was recognized after the infusion of neuron exiting aminiacids. But the thereshouled for induction of potential change was very different from dog to dog. And the effect of infusion have continued for long time.Conclusions: Although we think that the preoperative infusion of neuro exciting aminoacids may be useful of detecting intercostal aretries to be reconstructed, we could not decide whether the effect was derived by the variation of arterial network because the reaction severity was very different from dog to dog. And the long lasting effect of infusing aminoacids must be the adverse effect for clinical use.
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