The study of re-carcification of infected dentine

在传统的龋病治疗方法中，要求被感染的牙本质被完全去除。在某些情况下，牙髓被去除，结果牙齿的寿命变得更短。最近，最小干预牙科被推荐。本研究对感染牙本质的再钙化进行了研究。研究了含抗菌药物的玻璃离子修复体的性能。骨水泥中混合药物含量越多，对BHI血琼脂的抑制率越大。然而，这也导致水泥的力学和物理性能下降。研究了氟化粘接修复树脂材料和新研制的复合体中氟的释放、氟在牙周组织中的摄取及其耐酸性的影响。玻璃离子水门汀的氟离子释放量高于树脂和复合体。WDX分析显示，在去离子水中浸泡60天后，牙本质和牙釉质接触区的氟浓度。牙釉质、牙本质板与释氟修复材料接触后，其耐酸性增强。修复体边缘存在龋病的可能性较高，使用含氟粘结材料可降低这种可能性，防止牙釉质和牙本质修复边缘周围发生继发性或初发性龋病。此外，这项研究还表明，使用氟化物释放材料可以使受感染的牙本质重新矿化。提示激光龋病检测系统是评价牙齿再矿化的有效手段。

In conventional procedure of caries treatment, it is demanded that the infected dentin is completely removed. In some case, the pulp was removed, as a result, the life of teeth was became shorter. Recently, minimal intervention dentistry is recommended. In this study, re-carcification of infected dentine was studied. The properties of glass-ionomer restorative cements containing mixed antibacterial drugs were studied. The more amount of mixed drugs contained in cements, the greater inhibition zone on BHI blood agar was observed. However, this also resulted in decreased mechanical and physical propertied of cements. The fluoride release from fluoridated adhesive restorative resin materials and new developed Compomer, fluoride uptake into surrounding tooth structures and the effect of their acid resistance were investigated. Glass-ionoomer cements showed higher fluoride release than those of resin and Compomer. WDX analysis showed the fluoride concentration on dentin and enamel contact area, after 60 days of immersion in deionized water. The acid resistance of enamel and dentin plates which contact with fluoride releasing restorative materials was increased. There is a higher possibility for the presence of caries around margins of restorations, application of fluoridated adhesive materials will lower this possibility and prevent secondary or initial caries around the margins of the restorations in both enamel and dentin. Also, this study showed the infected dentin is re-mineralized using the fluoride releasing materials. It was suggested that a new detection system for caries using the laser apparatus is useful to evaluate the re-mineralization of tooth.