Molecularly Imprinted Membranes Having recognition Binding Sites for Environmental Wareogenic Chemicals as Utilized with Novel membrane Adsorbents

分子印迹膜与新型膜吸附剂一起使用，具有环境化学品的识别结合位点

• 批准号: 12650764
• 负责人: KOBAYASHI Takaomi
• 金额: $ 2.43万
• 依托单位: Nagaoka University of Technology
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2000
• 资助国家: 日本
• 起止时间: 2000 至 2002
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12650764/
• 关键词: Molecularly imprinting; Functional Membranes; Separation Membranes; Endocrine disrupter; Recognition; 内分泌攪乱; 鋳型; 濃縮; 環境汚染; 内分泌攪乱物質; 分解; 鋳型認識

We have developed non-covalent imprinting method for MIP preparation, which makes use of phase inversion process.<11> The resultant imprinting membranes showed permselective recognition to the target molecules and were very useful for selective binding and continuous operation to treat for large amounts of solute solution. Because of these advantages, it is very convenient to concentrate environmental pollutant compounds, which are present in extreme dilute concentration in waste water. In the present report work, research effort was made aiming at using imprinted polymer membrane targeted to environmental estrogenic compounds and toxic chemicals. We concentrated on recognition properties of imprinted membranes and focused on how the imprinted membrane was functionalized on the recognition for their target chemicals by membrane adsorption.

我们发展了一种利用相转化法制备分子印迹聚合物的非共价印迹方法。<11>所得的印迹膜显示出对目标分子的选择性识别，并且非常适用于选择性结合和连续操作以处理大量溶质溶液。由于这些优点，浓缩在废水中以极稀浓度存在的环境污染物化合物是非常方便的。本论文的研究工作主要是针对环境雌激素类化合物和有毒化学品，利用分子印迹聚合物膜进行检测。重点研究了分子印迹膜的识别性能，重点研究了分子印迹膜如何通过膜吸附功能化来实现对目标化合物的识别。

项目成果

Takaomi Kobayashi: "Molecualrly Imprinted Membranes Having Amphiphilic Scaffold Media for Target Molecule"Mater. Res. Soc. Proc. AA, Membrane-Prearation, Properties and Applications. 752. AA521-AA525 (2003)

Takaomi Kobayashi：“具有目标分子两亲支架介质的分子印迹膜”Mater。

Takaomi Kobayashi, P. Sreenivasulu Reddy, Masanori Abe, Mitiharu Ohta, Nobuyuki Fujii: "Molecularly Imprinted Polysulfone Membranes with Acceptor Sites for Donor Dibenzofuran as a Novel Membrane Adsorbents: Charge Transfer Interaction for Recognition Orig

Takaomi Kobayashi、P. Sreenivasulu Reddy、Masanori Abe、Mitiharu Ohta、Nobuyuki Fujii：“具有供体二苯并呋喃受体位点的分子印迹聚砜膜作为新型膜吸附剂：用于识别起源的电荷转移相互作用

Takaomi Kobayashi: "Ultrasoundly Enhanced Membrane Treatment for Hollow Fiber Microfiltration in Controlled Sonic Field"Jpn. J. Appl. Phys.. (印刷中). (2003)

Takaomi Kobayashi：“受控声场中的中空纤维微滤的超声增强膜处理”Jpn.Appl.（出版中）。

Takaomi Kobayashi: "Phase Inversion Molecular Imprinting by Using Template Copolymerized Polymers for High Substrate recognition"Langmuir. 18. 2866-2872 (2002)

Takaomi Kobayashi：“利用模板共聚聚合物进行相反转分子印迹以实现高底物识别”Langmuir。

T.Kobayashi el al.: "Molecular Imprinting of Caffeine and Its recognition assay by quartz Crystal microbalance"Analytica Chimica Acta. 435巻1号. 141-149 (2001)

T.Kobayashi 等：“咖啡因的分子印迹及其通过石英晶体微量天平的识别测定”Analytica Chimica Acta，第 435 卷，第 1. 141-149 期（2001 年）