molecularly imprinted Filters having Selective Recognition and Adsorption properties to Targeted Molecules of Environmental Estrogenetic nature.

分子印迹过滤器对环境雌激素性质的目标分子具有选择性识别和吸附特性。

• 批准号: 15310034
• 负责人: KOBAYASHI Takaomi
• 金额: $ 10.18万
• 依托单位: Nagaoka University of Technology
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2003
• 资助国家: 日本
• 起止时间: 2003 至 2005
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15310034/
• 关键词: Molecularly imprinting; Filters; Membranes; Separation; Endcrine disruptor; Recognition; Adsorption; Tailor-made; 内分泌撹乱物質; 物質分離; 吸着; 環境浄化; 膜; 物質認識機; フイルタ; 鋳型; 多孔性

Design approaches for molecular imprinting polymers are to be novel for filters having biological macromolecule binding sites complementary to the target environmental disruptors. Therefore, we have developed non-covalent imprinting method for MIP preparation, which makes use of phase inversion process. The resultant imprinting membranes showed permselective recognition to the target molecules and were very useful for selective binding and continuous operation to treat for large amounts of solute solution. Therefore, we concluded that because of these advantages, it is very convenient to concentrate environmental pollutant compounds, which are present in extreme dilute concentration in waste water. Therefore, selective adsorption of such toxic compound by MIP membrane materials is considered increasingly useful for toxic removal from waste solution. In the present report work, research effort was made aiming at using imprinted polymer filters targeted to environmental estrogenic compou … More nds and toxic chemicals. We concentrated on recognition properties of imprinted membranes and focused on how the imprinted membrane was functionalized on the recognition for their target chemicals by membrane adsorption. :(1) Bisphenol A Imprinted Polymer Adsorbents with Selective Recognition and Binding Characteristics.(2) Hybrid molecularly imprinted membranes for targeted bisphenol derivatives : Bisphenol A (BPA) imprinted polymer, which was prepared with (1) process was hybridized for porous membrane scaffolding of polystyrene (PS), cellulose acetate (CA), nylon 66 (Ny) and polysulfone (PSf) by phase inversion technique,(3) Hybrid molecularly imprinted polymer membranes targeted to indole template was presented. By using 3-indoleethylmethacrylate (IEMA) via esterification of 3-indoleethanol (IE) and methacrylic acid chloride.(4) Porous Imprinted Polymer Membranes Prepared were with Phase Separation in Compressed Carbon Dioxide.(5) Molecular imprinted copolymers, which highly recognized and bound bile acid (BA), were synthesized using covalently imprinting technique.(6) Phase inversion molecular imprinting by using template Nylons for high phenyl alanine recognition was investigated. Less

分子印迹聚合物的设计方法对于具有与目标环境干扰物互补的生物大分子结合位点的过滤器是新颖的。因此，我们开发了一种利用相转化法制备分子印迹聚合物的非共价印迹方法。所得的印迹膜显示出对目标分子的选择性识别，并且非常适用于选择性结合和连续操作以处理大量溶质溶液。因此，我们得出结论，由于这些优点，它是非常方便的浓缩环境污染物的化合物，这是目前在极端稀释浓度的废水。因此，MIP膜材料对这种有毒化合物的选择性吸附被认为越来越适用于从废液中去除有毒物质。本论文的研究工作主要是利用印迹聚合物膜对环境雌激素类化合物进行检测， ...更多信息 nds和有毒化学品。重点研究了分子印迹膜的识别性能，重点研究了分子印迹膜如何通过膜吸附功能化来实现对目标化合物的识别。（1）具有选择性识别和结合特性的双酚A印迹聚合物吸附剂。(2)以双酚A（BPA）为模板分子的杂化分子印迹膜：（1）采用相转化法将双酚A（BPA）分子印迹聚合物与聚苯乙烯（PS）、醋酸纤维素（CA）、尼龙66（Ny）和聚砜（PSf）多孔膜骨架进行杂化，（3）制备了以吲哚为模板分子的杂化分子印迹聚合物膜。通过使用3-吲哚乙基甲基丙烯酸酯（IEMA），经由3-吲哚乙醇（IE）和甲基丙烯酸氯的酯化反应。(4)压缩二氧化碳中相分离法制备多孔印迹聚合物膜。(5)采用共价印迹技术合成了对胆汁酸具有高度识别和结合能力的分子印迹聚合物。(6)研究了以尼龙为模板的转相分子印迹对苯丙氨酸的高分子识别。少

项目成果

分子認識捕捉機能を有するポリマー組成物及び当該組成物を使用するポリマー成形体の製造法

具有分子识别捕获功能的聚合物组合物以及使用该组合物的聚合物成型品的制造方法

• 发表时间: 2004

Shao Ling Xia, Hong Ying Wang, Takaomi Kobayashi: "Moleculaely Imprinted Materials-2003"Phase Inversion Molecularly Imprinting of Uracil Targeted Membranes Made of Polyacrylo nitrile Copolymers Having Methacrylic Acid and Acrylic Acid Segments for Recogni

夏少凌，王红英，小林高臣：“分子印迹材料-2003”具有甲基丙烯酸和丙烯酸片段的聚丙烯腈共聚物制成的尿嘧啶靶向膜的反相分子印迹用于识别

Hybrid-sol Gel Membranes of Polyacrylonitrile-tetraethoxysilane Composites for Gas Permselectivity.

用于气体选择性渗透的聚丙烯腈-四乙氧基硅烷复合材料的混合溶胶凝胶膜。

• 发表时间: 2003
• 期刊: J.Appl.Polym.Sci. 88
• 作者: Minoru Iwata;Takeharu Adachi;Miwa Tomidokoro;Mitiyoshi Ohota;Takaomi Kobayashi
• 通讯作者: Takaomi Kobayashi

T.Kobayashi, T.Onodera: "Molecularly Imprinted Membranes Having Amphiphilic Functional Moieties by Phase Inversion"Advances in Technology of Materials & Materials Processing Journal. (印刷中). (2004)

T.Kobayashi、T.Onodera：“通过相转化实现具有两亲性功能部分的分子印迹膜”《材料技术进展》和材料加工杂志（2004 年出版）。

Scaffold imprinting, Chapter 10 (Molecularly Imprinted Materials : Science and Technology.)

支架压印，第 10 章（分子压印材料：科学与技术。）

• 发表时间: 2004
• 作者: Minoru Iwata;Takeharu Adachi;Miwa Tomidokoro;Mitiyoshi Ohota;Takaomi Kobayashi;Minoru Iwata;Takeharu Adachi;Miwa Tomidokoro;Mitiyoshi Ohota;Takaomi Kobayashi;Takaomi Kobayashi
• 通讯作者: Takaomi Kobayashi