The change of cortical motor neuron excitability in periphearl nerve injury

周围神经损伤时皮质运动神经元兴奋性的变化

• 批准号: 12671419
• 负责人: KANEKO Kazuo
• 金额: $ 1.6万
• 依托单位: Yamaguchi University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2000
• 资助国家: 日本
• 起止时间: 2000 至 2002
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-12671419/
• 关键词: motor neuron; cortex; magnetic stimulation; evoked spinal cord potentials; peripheral nerve injury; 大脳運動神経; 末梢神経; 運動ニューロン

To investigate changes in cortical motor neuron excitability after peripheral nerve injury, evoked spinal cord potentials (ESCPs) following hemispheric transcranial magnetic stimulation (TMS) were recorded in awaken patients with unilateral brachial plexus injury. No significant change was observed in the threshold of ESCPs following TMS contra-lateral to the injured upper limb compared to that following TMS contra-lateral to the intact upper limb. Several ESCP components were recorded following high stimulus hemispheric TMS. No significant changes were observed in comparison with number, latency and amplitude of ESCPs following high stimulus TMS contra-lateral to the injured upper limb and those following TMS contra-lateral to the intact upper limb.Conclusion: From a study of ESCPs following single TMS, no evidence was obtained that cortical motor neuron excitability changes in patients with traumatic unilateral brachial plexus injury at relatively early stages.

为探讨周围神经损伤后皮质运动神经元兴奋性的变化，对单侧臂丛神经损伤苏醒患者行半球经颅磁刺激(TMS)后记录脊髓诱发电位(ESCP)。损伤上肢对侧TMS组与完好上肢对侧TMS组比较，ESCP阈值无明显变化。在高刺激半球TMS后，记录了几个ESCP成分。结论：单侧TMS术后皮层运动神经元兴奋性未见明显改变。

项目成果

Kazuo, Kaneko et al.: "Does cortical motor neuron excitability change in peripheral nerve injury?"Clinical Neurophysiology. 114(4). 596-599 (2003)

Kazuo，Kaneko 等人：“周围神经损伤时皮质运动神经元兴奋性是否发生变化？”临床神经生理学。

金子和生 他: "末梢神経損傷例における大脳運動ニューロンの興奮性の変化"整形外科と災害外科. 51. 367-369 (2001)

Kazuo Kaneko 等人：“周围神经损伤时大脑运动神经元兴奋性的变化”《骨科和灾难外科》51. 367-369 (2001)。

Kazuo Kaneko et al.: "Does cortical motor neuron excitability change in peripheral nerve injury?"Clinical Neurophysiology. 114. 596-599 (2003)

Kazuo Kaneko 等人：“周围神经损伤时皮质运动神经元兴奋性是否发生变化？”临床神经生理学。

Kazuo Kaneko et al.: "Dose cortical motor neuron excitability change in peripheral neuropathy?"Clinical Neurophysiology. (印刷中). (2003)

Kazuo Kaneko 等人：“周围神经病中皮质运动神经元兴奋性的变化？”临床神经生理学（2003 年出版）。

Kazuo, Kaneko et al.: "Cortical motor neuron excitability in patients with peripheral nerve injury"Seikeigeka to Saigaigeka. 51(2). 367-369 (2002)

Kazuo、Kaneko 等人：“周围神经损伤患者的皮质运动神经元兴奋性”Seikeigeka 到 Saigaigeka。