Three-dimensional imaging analysis about affinity between jawbones and ultra thin-hvdroxv-apatite-coated implant

将超薄羟基磷灰石涂层（HA）和纯钛（Ti）种植体植入犬颌骨内，通过组织标本和micro-CT三维图像，及时观察种植体内及近表面骨融合形态的变化。并利用试制的差异管理软件对临床病例的骨结构变化进行分析。充填种植体后，动物实验3 ~ 24周，临床病例1年。对于该病例中的新活骨添加，不仅种植体基底向上1/2的母基底骨表面，而且HA膜表面也被认为是具有代表性的，例如在三周后用HA进行显微镜检查。在Ti中，这种现象仅出现在另一个地板骨的表面。种植体表面有纤维连接组织进入。种植体底部向下无差异 ...更多信息 HA和Ti之间的1/2。5周后，种植体底部向上1/2的骨间隙被HA完全封闭，新的生骨加入另一个底部骨表面。另一方面，这个空间是不满意的与新的生骨Ti，和纤维连接组织层。尽管担心三周后会出现伪影，但可以从所有角度的代表性显微CT视图中捕获骨和植入体的边界。虽然两种种植体在种植体底部向上1/2处的骨间隙内均存在骨丢失，但这种趋势与Ti有关。HA骨髓腔内可见骨小梁样结构形成，并与皮质骨相连。另一方面，它不在钛植入物周围。在临床病例中，使用差异管理的试验软件对与骨变化区域相对应的像素数进行计数。骨吸收和骨重建之间的区别是困难的，但定量可以确定骨变化的区域。少

Ultrathin-Hydroxyapatite-coated (HA) and pure titaniumsimple (Ti) implantswere filied up in the jawbone of dogs, and a newly liveprocess and a change of the bone fusion form in and near surfaces part of implant were timelyobserved using the organization specimen and the micro-CT three-dimensional image. Moreover,the difference management software of the trial production was used to analyze a change of bone structure of theclinicalcase. After fillingimplant, itwas relatedfrom3weeks to24weeksduringtheanimal experiment,and for 1 year in the clinical cases. As for thenewly livebone addition in the case, not only the surface of the mother floor bone of implant floor upward 1/2 but also the surface of aHA filmwas recognized as the representative for example of amicroscopic examinationwith HAafter threeweeks. In Ti, this phenomenon presented on only the surface of themother floor bone. On the surface of implant, fibre-connecting-tissue entered. Therewas no difference in implant floor downward … More 1/2 betweenHA and Ti. As the case after 5 weeks, the bone space of implant floor upward 1/2 was closed with HA by perfection by the newly raw bone added on the surfaceof themother floor bone. On theother hand, this spacewasn't satisfiedwithTi in thenewly rawbone, and fibro-connecting tissue lay. Though it was apprehensive for the occurrence of artifact after three weeks, a boundary with the bone and implant body could be caught with a representative example of themicro-CTviews from all angles. Though abone loss was admitted in the bone space of implant floor upward 1/2 onboth implant, the tendencywas expressedwithTi. The formationof the trabecular patternwas recognized in the marrow cavity with HA, and theywere connected to cortical bone. On the other hand, it was not in the surroundings of Ti implant. In clinical cases, the pixel number corresponding to the bone change area was counted using a trial software of the difference management. A distinction between bone absorption and remodeling was difficult, but quantitatively could specify the bone change area. Less