Three-dimensional imaging analysis about affinity between jawbones and ultra thin-hvdroxv-apatite-coated implant

颌骨与超薄羟基磷灰石涂层种植体亲和力三维成像分析

• 批准号: 13671980
• 负责人: WAKOH Mamoru
• 金额: $ 1.15万
• 依托单位: TOKYO DENTAL COLLEGE
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2001
• 资助国家: 日本
• 起止时间: 2001 至 2002
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-13671980/
• 关键词: ULTRA-THIN-HYDROXY-APATITE; IMPLANT; MICRO-CT; THREE-DIMENSIONAL IMAGES; DIGITAL IMAGES

Ultrathin-Hydroxyapatite-coated (HA) and pure titaniumsimple (Ti) implantswere filied up in the jawbone of dogs, and a newly liveprocess and a change of the bone fusion form in and near surfaces part of implant were timelyobserved using the organization specimen and the micro-CT three-dimensional image. Moreover,the difference management software of the trial production was used to analyze a change of bone structure of theclinicalcase. After fillingimplant, itwas relatedfrom3weeks to24weeksduringtheanimal experiment,and for 1 year in the clinical cases. As for thenewly livebone addition in the case, not only the surface of the mother floor bone of implant floor upward 1/2 but also the surface of aHA filmwas recognized as the representative for example of amicroscopic examinationwith HAafter threeweeks. In Ti, this phenomenon presented on only the surface of themother floor bone. On the surface of implant, fibre-connecting-tissue entered. Therewas no difference in implant floor downward … More 1/2 betweenHA and Ti. As the case after 5 weeks, the bone space of implant floor upward 1/2 was closed with HA by perfection by the newly raw bone added on the surfaceof themother floor bone. On theother hand, this spacewasn't satisfiedwithTi in thenewly rawbone, and fibro-connecting tissue lay. Though it was apprehensive for the occurrence of artifact after three weeks, a boundary with the bone and implant body could be caught with a representative example of themicro-CTviews from all angles. Though abone loss was admitted in the bone space of implant floor upward 1/2 onboth implant, the tendencywas expressedwithTi. The formationof the trabecular patternwas recognized in the marrow cavity with HA, and theywere connected to cortical bone. On the other hand, it was not in the surroundings of Ti implant. In clinical cases, the pixel number corresponding to the bone change area was counted using a trial software of the difference management. A distinction between bone absorption and remodeling was difficult, but quantitatively could specify the bone change area. Less

将超薄羟基磷灰石涂层(HA)和纯钛(Ti)种植体植入狗的颌骨内，利用组织标本和Micro-CT三维图像，实时观察种植体内部和近表面的新的活动过程和骨融合形式的变化。并利用试制的差异管理软件对临床病例骨结构的变化进行了分析。植入后，动物实验3周~24周，临床病例1年。对于病例中新增加的活骨，不仅种植体底向上1/2的母底骨表面，而且AHA膜表面在三周后被认为是HA显微镜检查的代表。在钛中，这种现象只出现在母体底骨的表面。种植体表面有纤维连接组织进入。种植体底向下…无差异羟基磷灰石和钛之间多1/2。5周后，种植体底上1/2以上的骨间隙用羟基磷灰石完美地闭合，在母体底骨表面添加新生骨。另一方面，新生骨和纤维连接组织层中的钛含量不能满足要求。虽然3周后出现伪影令人担忧，但通过从各个角度拍摄具有代表性的显微图像，可以捕捉到与骨和种植体的分界线。虽然两种种植体种植体底向上1/2的骨间隙均有骨质丢失，但钛表现出这一趋势。透明质酸可在骨髓腔内识别出骨小梁的形成，并与皮质骨相连。另一方面，它不在钛种植体周围。在临床病例中，使用差异管理的试验软件计算对应于骨变化区域的像素数。很难区分骨吸收和骨重建，但可以定量地确定骨改变的区域。较少

项目成果

WAKOH MAMORU: "Quantitative analysis of bone structure changesduring implant operation usins disital dental imasins system"Shikwa Gakuho. 102. 829 (2002)

WAKOH MAMORU：“使用远端牙科 imasins 系统对种植手术期间骨结构变化进行定量分析”Shikwa Gakuho。

矢島安朝: "超薄膜HAコーティングインプラントの臨床使用経験"日本口腔外科学会誌. 47. 1066-1066 (2001)

Yasutomo Yajima：“超薄 HA 涂层种植体的临床经验”日本口腔颌面外科杂志 47. 1066-1066 (2001)。

和光 衛: "インプラント術前画像検査におけるCT画像の有用性"国際歯科学士会雑誌(J.I.C.D). 33巻(未定). (2002)

Mamoru Wako：“CT 图像在种植前影像检查中的实用性”《国际牙科学会杂志》(J.I.C.D) 第 33 卷（待定）。

山内智博: "超薄膜HAコーティングインプラントの骨形成過程に関する実験的研究"日本口腔外科学会誌. 47. 1066-1066 (2001)

Tomohiro Yamauchi：“超薄 HA 涂层种植体骨形成过程的实验研究”日本口腔颌面外科学会杂志 47. 1066-1066 (2001)。

YAMAUCHI TOMOHIRO: "Experimental study about utility of ultrathinhidroxyapatite-coated implant"J.A.M.I. 1. 11-16 (2002)

山内智宏：“关于超薄羟基磷灰石涂层植入物实用性的实验研究”J.A.M.I.