A prospective study of depressed outpatients who visited the internal psychosomatic medicine
就诊于内科心身医学科的抑郁症门诊患者的前瞻性研究
基本信息
- 批准号:13672361
- 负责人:
- 金额:$ 1.41万
- 依托单位:
- 依托单位国家:日本
- 项目类别:Grant-in-Aid for Scientific Research (C)
- 财政年份:2001
- 资助国家:日本
- 起止时间:2001 至 2002
- 项目状态:已结题
- 来源:
- 关键词:
项目摘要
(1) The relationship between the types of depression and the outcomeWe studied prospectively the relationship between the types of depression and the outcome. Subjects were recruited from outpatients visiting for the first time the Department of Psychosomatic Medicine, Kyushu University Hospital from December 1, 1999 to May 31, 2000. One hundred and fifty-seven patients met the DSM-IV diagnosis criteria of major depressive disorder, dysthymic disorder, adjustment disorder with depressive mood and depressive disorder not otherwise specified. Of these, 65 patients adequately completing treatment during the 6 months were available. We conducted follow-up evaluations at 1, 3 and 6 months after the baseline assessment using Hamilton Depression Rating Scale (HAM-D) and Zung Self-rating Depression Scale. All types of depression showed clinically significant decreases on the HAM-D scores at 3 months after and further improvements at 6-month follow-up. We discussed the meaning of treating depressed patients at the internal psychosomatic medicine.The cost-effectiveness in treatment of depressed patients in internal psychosomatic medicineThe costs of our treatment were higher in depressed outpatients who had never been treated than in those who had been treated. However, the outcome was better in the former than in the latter. Thus, the cost-effectiveness of psychosomatic therapy in depression was higher in untreated patients than in those who had ever been treated. We conclude that proper diagnosis and treatment in early stage of depression brought higher cost-effectiveness.
(1)抑郁症类型与预后的关系我们前瞻性地研究了抑郁症类型与预后的关系。受试者从1999年12月1日至2000年5月31日第一次访问九州大学医院心身医学科的门诊患者中招募。157例患者符合DSM-IV诊断标准,包括重度抑郁障碍、心境恶劣障碍、伴抑郁情绪的适应障碍和未另行说明的抑郁障碍。其中,65例患者在6个月内充分完成治疗。采用汉密尔顿抑郁量表(HAM-D)和Zung抑郁自评量表(SDS)分别于治疗后1、3、6个月进行随访。所有类型的抑郁症在3个月后的HAM-D评分均显示出临床显著性下降,并在6个月随访时进一步改善。本文探讨了心身内科治疗抑郁症的意义,心身内科治疗抑郁症的成本-效果分析:门诊未治疗抑郁症患者的治疗费用高于已治疗抑郁症患者。然而,前者的结果优于后者。因此,心身治疗抑郁症的成本效益在未经治疗的患者中高于那些曾经接受过治疗的患者。结论:抑郁症的早期诊断和治疗具有较高的成本效益。
项目成果
期刊论文数量(23)
专著数量(0)
科研奖励数量(0)
会议论文数量(0)
专利数量(0)
Ando, T., et al.: "5-HT2A promoter polymorphism is not associated with aonrexia nervosa in Japanese patients"Psychiatric Genetics. 11. 157-160 (2001)
Ando, T. 等人:“5-HT2A 启动子多态性与日本患者的神经性厌食症无关”《精神病遗传学》。
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Komaki, G., et al.: "Orexin-A and leptin change inversely in fasting non-obese subjects"Eur J Endocrinol. 144. 645-651 (2001)
Komaki, G., et al.:“Orexin-A 和瘦素在禁食非肥胖受试者中呈相反变化”Eur J Endocrinol。
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野崎剛弘(久保木富房編): "食べられないやめられない"日本評論社. 240 (2002)
野崎武宏(久保木富房主编):“不能吃,不能停止”Nippon Hyoronsha 240 (2002)。
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Sudo, N., et al.: "An oral introduction of intcstinal bacteria prevents the development of a long-term Th2-skewed immunological memory induced by neonatal antibiotic treatment in mice"Clin Exp Allergy. 32. 1112-1116 (2002)
Sudo, N. 等人:“口服肠道细菌可防止小鼠新生抗生素治疗诱导的长期 Th2 倾斜免疫记忆的发展”Clin Exp Allergy。
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Kawai, K., et al.: "Aggressive behavior and serum testosterone concentration during the maturation process of male mice: the effects of fetal exposure to bisphenolA."Environmental Health Perspectives. 77. 292-299 (2003)
Kawai, K. 等人:“雄性小鼠成熟过程中的攻击行为和血清睾酮浓度:胎儿接触双酚 A 的影响。”环境健康观点。
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NOZAKI Takehiro其他文献
NOZAKI Takehiro的其他文献
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{{ truncateString('NOZAKI Takehiro', 18)}}的其他基金
The cost-effectiveness of a psychosomatic medicine-based approach to the treatment of type 2 diabetic patients : a prospective study
基于心身医学的方法治疗 2 型糖尿病患者的成本效益:一项前瞻性研究
- 批准号:
15590600 - 财政年份:2003
- 资助金额:
$ 1.41万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
胎生期及び新生児期の母仔環境が成長後の生体調節系に及ぼす影響に関する基礎研究
胎儿及新生儿期母婴环境对生长后生物调节系统影响的基础研究
- 批准号:
10670905 - 财政年份:1998
- 资助金额:
$ 1.41万 - 项目类别:
Grant-in-Aid for Scientific Research (C)
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