Periodic accord template polymerization by using helical supramolecular structures and Construction of complementary supramolecular ambiance

螺旋超分子结构的周期性一致模板聚合及互补超分子氛围的构建

• 批准号: 15350070
• 负责人: MIYATA Mikiji
• 金额: $ 9.54万
• 依托单位: Osaka University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2003
• 资助国家: 日本
• 起止时间: 2003 至 2005
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-15350070/
• 关键词: template polymerization; helical supramolecular structure; chirality; X-ray single crystallographic analysis; chiral crystal; complementary; steroid; alkaloid; 周期構造; 結晶構造解析; 超分子キラリティー; 水素結合; ジエン誘導体

Steroidal bile acids and their derivatives were established to have abilities for including organic substances. The breakthrough was the discovery of channel-type inclusion compounds of cholic acid. The subsequent studies provided us a chance for considering the concept that chiral carbon-chains can serve as information carriers, and express the information through their molecular assemblies. This concept gives the idea that the present informative materials such as proteins, nucleic acids, sugars are modified from the chiral carbon-chains. In other words, amide groups of proteins are not necessarily indispensable. The informative molecules have multiple hydrogen bonding groups which play an important role in determining structures of their assemblies. When we use bile acids and their derivatives, we can count kinds of combinations among the multiple hydrogen bonding groups in their assemblies. This paper deals with the structural study on the steroidal assemblies and the analogy to proteins.

已证实甾体胆汁酸及其衍生物具有包合有机物质的能力。突破性进展是胆酸通道型包合物的发现。随后的研究为我们考虑手性碳链作为信息载体，通过分子组装来表达信息的概念提供了机会。这一概念给出了这样的想法，即目前的信息材料如蛋白质、核酸、糖是从手性碳链修饰而来的。换句话说，蛋白质的酰胺基团不一定是必不可少的。信息分子具有多个氢键基团，这些氢键基团在决定其组装体的结构中起重要作用。当我们使用胆汁酸及其衍生物时，我们可以计算出它们组装体中多个氢键基团之间的各种组合。本文介绍了甾体组装体的结构研究及其与蛋白质的类比。

项目成果

Organic Layered Crystals with Adjustable Interlayer Distances of 1-Naphthylmethylammonium n-Alkanoates

层间距可调的1-萘基甲基正链烷酸铵有机层状晶体

• 发表时间: 2004
• 期刊: J.Amer.Chem.Soc. 126(6)
• 作者: Kazunori Nakano;Kazuki Sada;Kenji Nakagawa;Kazuaki Aburaya;Nungruethai Yoswathananont;Norimitsu Tohnai;Mikiji Miyata;T.Watabe;Y.Mizobe;K.Kato;K.Sada;N.Yoswathananont;S.Phongtamrug;K.Nakano;P.Dastidar;Takahito Itoh;Takahito Itoh;Katsunari Inoue;Rangrong Yoksan;Shinji Nomura;Kazuki Sada
• 通讯作者: Kazuki Sada

Well-defined Ion-pair Clusters of Alkyl- and Dialkylammonium Salts of a Sterically-hindered Carboxylic Acid. Implication for Hydrogen-bonded Lys Salt Bridges

位阻羧酸的烷基和二烷基铵盐的明确离子对簇。

• 发表时间: 2004
• 期刊: Chem.Lett. 33(2)
• 作者: Kazunori Nakano;Kazuki Sada;Kenji Nakagawa;Kazuaki Aburaya;Nungruethai Yoswathananont;Norimitsu Tohnai;Mikiji Miyata;T.Watabe;Y.Mizobe;K.Kato;K.Sada;N.Yoswathananont;S.Phongtamrug;K.Nakano;P.Dastidar;Takahito Itoh;Takahito Itoh;Katsunari Inoue;Rangrong Yoksan;Shinji Nomura;Kazuki Sada;Kazuaki Kato;Kazuaki Kato;Kazunori Nakano;Kazuaki Kato;Kazuki Sada
• 通讯作者: Kazuki Sada

Helical Tape Assemblies in Inclusion Crystals of Bile Acids and Their Derivatives. Implication for hydrogen-bonded Lys salt bridges.

胆汁酸及其衍生物包合物晶体中的螺旋带组件。

• 发表时间: 2004
• 期刊: Journal of Inclusion Phenomena and Macrocyclic Chemistry 48(1)
• 作者: Akikazu Matsumoto;Akinori Matsumoto;Takafumi Kunisue;Akira Tanaka;Norimitsu Tohnai;Kazuki Sada;Mikiji Miyata;K.Inoue;K.Kato
• 通讯作者: K.Kato

Interpretation of Enantioresolution in Nordeoxycholic Acid Channels Based on the Four-location Model

基于四位置模型的去甲脱氧胆酸通道对映体拆分解释

• 发表时间: 2003
• 期刊: Chirality 15(1)
• 作者: Akikazu Matsumoto;Akinori Matsumoto;Takafumi Kunisue;Akira Tanaka;Norimitsu Tohnai;Kazuki Sada;Mikiji Miyata;K.Inoue;K.Kato;K.Sada;Kazuaki Kato;Kazuaki Kato;Kazuaki Kato
• 通讯作者: Kazuaki Kato

Stabilization of Vinyl Chloride Monomer via Guest Adsorption Process in Cholic Acid Guest-Free Channel and Its Inclusion Polymerization

胆酸无客体通道中客体吸附过程稳定氯乙烯单体及其包合聚合

• 发表时间: 2003
• 期刊: Radiation J.Polymer Anal.Charact. 8
• 作者: Suwabun Chirachanchai;Nattha Chiravanichanun;Mikiji Miyata
• 通讯作者: Mikiji Miyata