A general research in order to evaluate the metabolic risk of obesity in children and effect of health support program for them.

在日本学龄儿童中，儿童肥胖的患病率和代谢综合征（MS）的风险正在增加。在成人中，肥胖，如高水平的中央体脂肪，特别是内脏脂肪组织（VAT），与冠心病、高血压和非胰岛素依赖型糖尿病的危险因素有关。本研究的目的是评估肥胖儿童的代谢风险和增值区，以及健康支持计划对他们的影响。在这篇综述中，我们将重点关注肥胖儿童VAT与MS之间的关系。我们对392例6 ~ 14岁肥胖儿童（男孩212例，女孩174例）的VAT面积与MS的关系进行了研究。在脐部水平通过计算机断层扫描测量VAT和皮下脂肪组织（SAT）。MS的参数采用血压（收缩压、舒张压）和临床血液生化。利用受试者工作特征（ROC）曲线分析，计算代谢紊乱的阈值。除年龄影响外，VAT区与男女患者TG、HDL-c、收缩压、舒张压、丙氨酸转氨酶、尿酸密切相关。Pearson相关系数值女生高于男生。男孩的敏感性和特异性均为70%，女孩的敏感性和特异性分别为70%和90%。男孩和女孩的增值税面积阈值均为55cm^2。这些结果表明，VAT面积阈值（55cm^2）可以将儿童肥胖分为有医学问题和无医学问题。

The prevalence of pediatric obesity and the risk of metabolic syndrome (MS) are increasing in Japanese school children. In adults, obesity such as high levels of central body fatness, especially visceral adipose tissue (VAT), are associated with risk factors for coronary heart disease, hypertension, and non insulin-depended diabetes mellitus. The purpose of the present research was to evaluate the metabolic risk and VAT area in obese children and effect of health support program for them. In this summary, we will focus our attention on the relationship between VAT and MS in obese children.We examined the relationship between VAT area and MS in 392 (boys 212, girls 174) obese children 6 to 14 years old. VAT and subcutaneous adipose tissue (SAT) were measured by computed tomography at the level of the umbilicus. The parameters of MS were used of blood pressure (SBP and DBP) and clinical blood biochemistry. A threshold value of metabolic derangement was calculated, using the analysis of receiver operating characteristic (ROC) curve.VAT area was closely associated TG, HDL-c, SBP, DBP, alanine aminotransferase, and uric acid in boys and girls except the influence of age. Pearson's correlation coefficient values were higher in girls than in boys. VAT gave 70% sensitivity and specificity in boys, and 70% sensitivity and 90% specificity in girls. The threshold values for VAT area were 55cm^2 in both boys and girls.These results suggested that threshold values of VAT area (55cm^2) be able to classify childhood obese type into with medical problem and those without.