NSERC-DFG SUSTAIN: Electroreductions of C=O bonds catalyzed by borohydrides

NSERC-DFG SUSTAIN：硼氢化物催化的 C=O 键电还原

• 批准号: 534359418
• 负责人: Professorin Dr. Inke Siewert
• 金额: --
• 依托单位: Department of Chemistry
• 依托单位国家: 德国
• 项目类别: Research Grants
• 资助国家: 德国
• 项目状态: 未结题
• 来源: https://gepris.dfg.de/gepris/projekt/534359418?language=en
• 关键词: NSERC; DFG; SUSTAIN; Electroreductions; C=O

Boron-based hydrides such as [R3BH]−, R = organic group, are effective stoichiometric hydride transfer reagents with high hydricities. They are widely used in synthetic chemistry for the reduction of carbonyl compounds. However, the high energy cost associated with their multistep preparations, starting from alkali metals, precludes their large-scale implementation. We will target in our 3-year program the electrochemical synthesis of borohydride catalysts for the hydrogenation of polar C=O bonds, such as those found in ketones, esters, and CO2. This is a unique and more sustainable approach to chemical synthesis as harmful waste associated with stochiometric use of chemical reductant is avoided.

硼基氢转移试剂，如[R3 BH]-，R =有机基团，是有效的化学计量的氢化物转移试剂，具有高的氢度。它们广泛用于合成化学中还原羰基化合物。然而，与从碱金属开始的多步制备相关的高能量成本排除了它们的大规模实施。我们将在我们的3年计划的目标是硼氢化物催化剂的电化学合成极性C=O键的氢化，如那些发现在酮，酯和CO2。这是一种独特且更可持续的化学合成方法，因为避免了与化学还原剂的化学计量使用相关的有害废物。