Elucidation of environmental and human emission by PBDDs/DFs and PXDDs/DFs in Japan

阐明日本 PBDD/DF 和 PXDD/DF 的环境和人类排放

• 批准号: 16390174
• 负责人: OHTA Souichi
• 金额: $ 4.22万
• 依托单位: Setsunan University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (B)
• 财政年份: 2004
• 资助国家: 日本
• 起止时间: 2004 至 2005
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-16390174/
• 关键词: PXDDs; DFs; PBDDs; Environmental Emission; Human contamination; Brominated flame retardants; Mother's milk contamination; Sediments contamination; Toxic evaluation; 臭素化ダイオキシン; 塩素・臭素化ダイオキシン; PBDDs; PBDFs; PXDDs; PXDFs

Polybrominated diphenyl ethers (PBDEs) and tetrabromobisphenol A (TBBPA) are used in large quantities as brominated flame-retardants (BFRs) to reduce the risk of fire in a wide range of manufacture products such as computers, furnitures, textiles and automobiles. Inaddition, there is sufficient evidence that the above similar process or incineration of consumer products containing such flame-retardant chemicals results in the formation of polybrominated dibenzo-p-dioxins/furans (PBDD/DFs) and monobromo-polychlorinated dibenzo-p-dioxins/furans (PXDD/DFs). These chemicals, as well as the BFRs, have been found to occur throughout the environment. And the intake of these contaminants from food, air and water is suspected to be the primary route of human. The levels of PCDDs/DFs, PXDDs/DFs and PBDDs/DFs in the sediments from Setouchi-Sea were compared. Almost was PCDDs/DFs, showing the levels of PCDDs/DFs (1.3 - 13 ng/gd.w)>PBDDs/DFs (15 - 16,000 pg/g d.w.)>PXDDs/DFs (1.0 - 90 pg/g d.w ). Especially, extreme high pollution by PBDDs /DFs was observed in the sample of Mizushima, and high concentrations of TeBDD/DF, PeBDD and HxBDD as 2,3,7,8-substituted isomer were detected.The TEQ levels of PCDDs/DFs, PXDDs/DFs and PBDDs/DFs in the mixed breast milk, cow's milk and powdered milk were investigated. Average TEQ concentration (20.3 pg TEQ/g lipid) in breast samples from primiparae was over two-fold against that (10.8 pg TEQ/g lipid) from multiparae. As an extremely interesting phenomenon, it was recognized that the ratio of PXDDs/DF for PCDDs/DFs calculated as TEQ concentration ranged between 4 and 46 %.

多溴二苯基醚（PBDES）和四抗苯酚A（TBBPA）大量使用，用作溴化的燃烧剂（BFR），以降低各种制造产品（例如计算机，酿酒厂，纺织品，纺织品和自动摩托车）在广泛的制造产品中发生火灾的风险。不成文中，有足够的证据表明，上述类似的含有这种燃烧性化学物质的消费产品的过程或焚化会导致形成多溴的二溴二苯二醇-P-二恶英/Furans（PBDD/DFS）和单型 - 多聚元素 - 洛杉矶 - 多聚氯的Dibenzo-p-Dioxins/furans/furans/furans/furans/furans（pxdd/ddfs）。这些化学物质以及BFR都在整个环境中发生。这些污染物从食物，空气和水中摄入的摄入量被怀疑是人类的主要途径。比较了Setouchi-SEA沉积物中的PCDD/DFS，PXDD/DFS和PBDDS/DFS的水平。几乎是PCDD/DFS，显示了PCDD/DFS（1.3-13 ng/gd.w）> pbdds/dfs（15-16,000 pg/g d.w。）> pxdds/dfs（1.0-90-90 pg/g d.w）的水平。特别是，在Mizushima样品中观察到PBDDS/DFS极高的污染，并且检测到高浓度的TEBDD/DF，PEBDD和HXBDD为2,3,7,8-8-8-溶解的异构体。来自Primiparae的乳腺样品中的平均Teq浓度（20.3 pg Teq/g脂质）与来自多毛的乳腺样本相比（10.8 pg teq/g脂质）超过两倍。作为一种非常有趣的现象，人们认识到，TEQ浓度计算的PXDDS/DF的PXDD/DF比率在4％至46％之间。