Exploring the gene regulation networks governing mitochondrial biogenesis in Arabidopsis

探索拟南芥线粒体生物发生的基因调控网络

• 批准号: DP0343849
• 负责人: A/Prof Patrick Finnegan
• 金额: $ 17.8万
• 依托单位: The University of Western Australia
• 依托单位国家: 澳大利亚
• 项目类别: Discovery Projects
• 财政年份: 2003
• 资助国家: 澳大利亚
• 起止时间: 2003-08-25 至 2006-08-24
• 项目状态: 已结题
• 来源: https://dataportal.arc.gov.au/RGS/Web/Grants/DP0343849
• 关键词: Exploring; gene; regulation; networks; governing

Mitochondria, subcellular organelles that perform many functions indispensable to plant growth and productivity, are dynamic compartments whose protein complement changes dramatically during plant development and under stress. Yet, the cellular processes that regulate the production of these organelles are virtually unknown. By combining conventional approaches with an extremely powerful holistic method for simultaneously examining the expression patterns of every gene in the model plant Arabidopsis, this project will identify proteins that regulate mitochondrial biosynthesis and uncover the gene networks that these proteins control. The project outcomes will provide new opportunities for the rational manipulation of plant growth and productivity.

线粒体是一种亚细胞细胞器，在植物生长和生产中发挥着重要作用，在植物生长发育过程中和逆境条件下，其蛋白质组成发生了显著变化。然而，调节这些细胞器产生的细胞过程几乎是未知的。通过将传统方法与一种非常强大的整体方法相结合，同时检查模式植物拟南芥中每个基因的表达模式，该项目将鉴定调节线粒体生物合成的蛋白质，并揭示这些蛋白质控制的基因网络。项目成果将为合理控制植物生长和生产力提供新的机会。