权益分类	功能权益	普通用户	{{item.name}}会员
{{category.name}}	{{benefitItem.name}}

Physiological and biochemical research for improvement of physical function in the elderly-Effect of concomitant treatment with exercise therapy and diet therapy-

改善老年人身体机能的生理生化研究-运动疗法与饮食疗法并用的效果-

基本信息

批准号：
17500474
负责人：
TAKATA Shingo
金额：
$ 2.01万
依托单位：
Okayama University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (C)
财政年份：
2005
资助国家：
日本
起止时间：
2005 至 2007
项目状态：
已结题

项目摘要

Physical function decreases in the elderly and the elderly have many chronic diseases. Treatment fur diseases and improvement of deconditioning is necessary for keeping health in the elderly. We investigated 【Research 1】 physiological and biochemical characteristics in the elderly with deconditioning, 【Research 2】 the effects of exercise therapy on deconditioning in the elderly and 【Research 3】 the effects of dietary supplementation on deconditioning in the elderly【Research 2】 Misasa Medical Center has spa and patients with chronic respiratory disease have spa therapy in our hospital Our previous studies have shown that subjective symptoms and ventilatory function are improved by spa therapy in patients with chronic obstructive pulmonary disease (COPD) because spa therapy improved mucociliary clearance and ventilatory dysfunction. We investigated the effects of spa therapy on six-minute walk distance in patients with COPD. We found that spa therapy improved Borg scale and six-minute walk distance in patients with COPD. The results demonstrated that spa therapy may lead to better exercise tolerance in patients with COPD.[Research 3] We have reported that spa therapy combined with dietary supplementation of perilla seed oil would be effective for patients with asthma, and would suppress the generation of leukotriene C4 (LTC4) by peripheral leucocytes. However, it is still unclear how the combination spa therapy and dietary supplementation of perilla seed oil influences on the pathophysiology of bronchial asthma. In the present study, the effects of spa therapy combined with dietary supplementation of perilla seed oil were examined in patients with asthma in relation to the serum eosinophil cationic protein (ECP) levels to investigate the effect on bronchial asthma. The results obtained here suggest that spa therapy combined with dietary supplementation of perilla seed oil leads to decrease in LTC_4, and ECP and improves pulmonary function and asthma control.

老年人身体机能下降，老年人有许多慢性病。治疗老年人的疾病，改善老年人的身体状况是保持老年人健康的必要条件。我们调查了[研究1]老年人的生理和生化特征，[研究2]运动疗法对老年人身体不适的影响[研究3]膳食补充剂对老年人身体不适的影响[研究2] Misasa医疗中心有水疗中心，慢性呼吸道疾病患者在我们医院接受水疗治疗，我们以前的研究表明，主观在慢性阻塞性肺疾病（COPD）患者中，通过水疗治疗改善了症状和排泄功能，因为水疗治疗改善了粘液纤毛清除和排泄功能障碍。我们调查了水疗对COPD患者6分钟步行距离的影响。我们发现，水疗改善COPD患者的博格量表和6分钟步行距离。结果表明，水疗疗法可能会提高COPD患者的运动耐力。[研究3]我们已经报道了水疗疗法结合紫苏籽油的膳食补充剂对哮喘患者有效，并且可以抑制外周血白细胞产生白三烯C4（LTC4）。然而，目前尚不清楚如何结合水疗疗法和紫苏籽油的饮食补充剂对支气管哮喘的病理生理学的影响。在本研究中，水疗结合膳食补充紫苏籽油的影响，在哮喘患者的血清嗜酸性粒细胞阳离子蛋白（ECP）水平进行了检查，以探讨对支气管哮喘的影响。本研究结果提示，水疗疗法结合紫苏籽油膳食补充可降低LTC_4和ECP，改善肺功能和哮喘控制。