Portable Noninvasive Positive Airway Device for COPD Patient Therapy

摘要 Koronis Biomedical Technologies建议开发并全面评估一种新颖的按需手持式双水平 治疗慢性阻塞性肺疾病（COPD）患者的BiPAP呼吸机 患有劳力性呼吸困难（“呼吸困难”）。众所周知，呼吸困难倾向于严重COPD 患者随着年龄的增长而不活动，导致外周肌肉失调，进一步增加 经历呼吸困难的风险，建立呼吸困难反复恐惧的恶性循环，进一步不活动， 潜在的社会隔离。拟议的双层快速紧急气道治疗（BREATHE）系统将 经过优化，可提供经验证的BiPAP治疗，在小型便携式 手持设备的外形。该系统将允许在旅途中进行治疗，解开患者的束缚，并增加他们的 有信心从事日常生活活动。

Abstract Koronis Biomedical Technologies proposes to develop and fully evaluate a novel, on-demand handheld bi-level positive airway pressure (BiPAP) ventilator to treat Chronic Obstructive Pulmonary Disease (COPD) patients suffering from exertional dyspnea (“breathlessness”). It is well known that dyspnea trends severe COPD patients as they age towards inactivity, resulting in peripheral muscle deconditioning that further increases the risk of experiencing dyspnea, establishing a vicious cycle of recurrent fear of dyspnea, further inactivity and potential social isolation. The proposed Bi-level Rapid Emergency Airway THErapy (BREATHE) system will be optimized to provide proven BiPAP therapy to rapidly relieve acute dyspnea in a miniaturized, portable handheld form factor. This system will allow for therapy on the go, untethering the patient and increasing their confidence to engage in activities of daily living.