Portable Noninvasive Positive Airway Device for COPD Patient Therapy

摘要 Koronis Biomedical Technologies建议开发并全面评估一种新的、按需手持两级 BiPAP呼吸机治疗慢性阻塞性肺疾病 患有劳力性呼吸困难(“呼吸困难”)。众所周知，呼吸困难会导致严重的慢性阻塞性肺疾病 患者随着年龄的增长而趋于不活动，导致外周肌肉去条件化，从而进一步增加 经历呼吸困难的风险，建立反复出现的对呼吸困难的恐惧的恶性循环，进一步的不活动和 潜在的社会孤立。拟议的二级快速紧急呼吸道治疗(呼吸)系统将是 优化提供成熟的BiPAP疗法，以快速缓解急性呼吸困难在微型，便携式 手持式外形。这个系统将允许在路上进行治疗，解除患者的束缚，增加他们的 有信心从事日常生活活动。

Abstract Koronis Biomedical Technologies proposes to develop and fully evaluate a novel, on-demand handheld bi-level positive airway pressure (BiPAP) ventilator to treat Chronic Obstructive Pulmonary Disease (COPD) patients suffering from exertional dyspnea (“breathlessness”). It is well known that dyspnea trends severe COPD patients as they age towards inactivity, resulting in peripheral muscle deconditioning that further increases the risk of experiencing dyspnea, establishing a vicious cycle of recurrent fear of dyspnea, further inactivity and potential social isolation. The proposed Bi-level Rapid Emergency Airway THErapy (BREATHE) system will be optimized to provide proven BiPAP therapy to rapidly relieve acute dyspnea in a miniaturized, portable handheld form factor. This system will allow for therapy on the go, untethering the patient and increasing their confidence to engage in activities of daily living.