Usefulness of laparoscopic surgery for colorectal cancer compared with open surgery

腹腔镜手术与开腹手术治疗结直肠癌的有效性

• 批准号: 17591416
• 负责人: INOMATA Masafumi
• 金额: $ 2.31万
• 依托单位: Oita University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2005
• 资助国家: 日本
• 起止时间: 2005 至 2007
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-17591416/
• 关键词: Colorectal Cancer; Laparoscopic Surgery; Open Surgery; Clinical Trial; Less Invasiveness; ランダム化試験

Objectives : Laparoscopic surgery technically is feasible for both benign and early staged cancer, it has not been widely accepted for advanced colon cancer and early and advanced rectal cancer. The aim of this study was to evaluate the short and long-term results of laparoscopic surgery for colorectal cancer.Materials and Methods : A phase III study included 32 patients undergoing laparoscopic or conventional open surgery for colon cancer. A phase II study included 16 patients undergoing laparoscopic surgery for rectal cancer. A short and long-term results were evaluated.Results: A phase III study demonstrated that blood loss was less, flatus returned more quickly, postoperative hospital stay was shorter in patients with laparoscopic than those with open surgery. There were no differences of intraoperative and postoperative complications. There were two patients with recurrence and no patients died. A phase II study demonstrated that there were no patients with conversion to open surgery, one with anastomatic bleeding, two with wound infection.Conclusions : Laparoscopic surgery for colorectal cancer was feasible in terms of safety and less invasiveness. Further examination of long-term outcome for advanced colon cancer should be needed.

目的：腹腔镜手术在技术上对良性肿瘤和早期肿瘤都是可行的，但对进展期结肠癌和早期及进展期直肠癌尚未被广泛接受。本研究的目的是评估腹腔镜手术结直肠cancer.Materials和方法的短期和长期的结果：第三阶段的研究包括32例接受腹腔镜或传统的开放手术结肠癌。一项II期研究包括16例接受腹腔镜直肠癌手术的患者。结果：III期临床研究显示，腹腔镜组患者术中出血量少，术后排气快，术后住院时间短。术中、术后并发症无差异。术后复发2例，无死亡病例。一项II期研究表明，有没有病人转换为开放手术，一个与腹腔镜出血，两个伤口infection.Conclusions：腹腔镜手术治疗结直肠癌是可行的安全性和微创。需要进一步检查晚期结肠癌的长期预后。

项目成果

Laparoscopic surgery of advanced colon cancer

晚期结肠癌的腹腔镜手术

• 发表时间: 2008
• 期刊: J Jpn Soc Endosc Surg 13(1)
• 作者: Masafumi;Inomata
• 通讯作者: Inomata

Laparoscopic surgery for advanced colon cancer

腹腔镜手术治疗晚期结肠癌

• 发表时间: 2006
• 作者: Seigo;Kitano;猪股 雅史;猪股 雅史;Masafumi Inomata
• 通讯作者: Masafumi Inomata

内視鏡外科手術はSSI発生を減少させうるか

内镜手术能否降低SSI的发生率？

• 发表时间: 2006
• 作者: Seigo;Kitano;猪股 雅史;猪股 雅史
• 通讯作者: 猪股 雅史

Current status of surgical site infection in laparoscopic Gastrointestinal surgery

腹腔镜胃肠手术手术部位感染现状

• 发表时间: 2005
• 作者: Masafumi;Inomata
• 通讯作者: Inomata

内視鏡外科における基礎研究の進歩

内镜外科基础研究进展

• 发表时间: 2007
• 期刊: 医学のあゆみ 220(8)
• 作者: Masafumi;Inomata;猪股 雅史
• 通讯作者: 猪股 雅史