Development of interventional program in health education for pre-diabetes mellitus

糖尿病前期健康教育干预方案的制定

• 批准号: 18500628
• 负责人: NOGI Akiko
• 金额: $ 2.53万
• 依托单位: Yamaguchi Prefectural University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2006
• 资助国家: 日本
• 起止时间: 2006 至 2007
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-18500628/
• 关键词: Pre-diabetes mellitus; Obesity; Insulin resistance; IGT; OGTT; Diet; Exercise; ブドウ糖負荷試験(OGTT); 食生活; 食後高血糖(IGT); 糖尿病; 栄養学; 行動学

Since the prevalence of diabetes mellitus are getting increase in Japanese; we conducted to develop an intervention al program for obesity based on health education and self-determination from 2000. We adopted the behavioral program to strengthen self-control of diet and exercise based on learning principles. Objectives of the program were to lose 1.0kg of weight and to reduce 10% of metabolic measurement values.Subjects were 123 residents with Body Mass. Index (BMI) of 26.1± 3.2, aged 57.2±8.1 years in Shimane Prefecture, voluntarily participated in the present study in 2006-2007. The behavioral intervention induced significant decrease s for intakes of energy (-483kcal, -22%), and increase for consumption of energy (146kcal, 6%) per day for participants. The intervention induced a significant difference in weight-loss (-2.8kg). Significant differences of anthropometric parameters were found in BMI (4.2%), waist circumference (4.2%), systolic blood pressure (2.9%), and lipid profile, such as total cholesterol (5.1%), triglyceride (22.0%) by the intervention. For participants.The participant numbers identified oral glucose tolerance test (OGTT) changed by the intervention, non glucose tolerance (NGT) increased (n=57 to 79), impaired fasting glucose (IFG) increased(n=6 to 11), impaired glucose tolerance (IGT) decreased(n=29 to 14), IFG+IGT increased (n=8 to 9) and type 2 diabetes mellitus (T2DM) decreased (n=14 to 10). Individuals with JOT showed significant differences in 2-h glucose (161mg/dl to 135mg/dl) and 30-min insulin (42.8μU/ml to 48.0μU/ml). also T2DM showed significant differences in homeostasis model assessment (HOMA-IR) (2.3 to L4), 30-min glucose (265mg/dl to 223mg/dl) and 2-h glucose (253mg/dl to 189mg/dl).This investigation suggests that the interventional program have an improvement of insulin resistance and an effect on early treatment for pre-diabetes mellitus.

由于日本糖尿病患病率呈上升趋势，从2000年开始，我们开展了以健康教育和自我决定为基础的肥胖干预计划。采用基于学习原则的行为程序，加强饮食和运动的自我控制。该计划的目标是体重减轻1.0公斤，代谢测量值减少10%。受试者为123名有体质量的居民。岛根县2006-2007年自愿参加本研究的儿童体重指数为26.1±3.2，年龄为57.2±8.1岁。行为干预使S每天的能量摄入量(-483千卡，-22%)显著降低，能量消耗(146千卡，6%)显著增加。干预导致的体重下降(-2.8公斤)有显著差异。干预后BMI(4.2%)、腰围(4.2%)、收缩压(2.9%)和血脂(如总胆固醇(5.1%)、甘油三酯(22.0%)等人体测量学参数有显著差异。受试者口服葡萄糖耐量试验(OGTT)的受试者人数发生改变，其中非糖耐量(NGT)增加(n=57~79)，空腹血糖受损(IFG)增加(n=6~11)，糖耐量受损(IGT)减少(n=29~14)，IFG+IGT增加(n=8~9)，2型糖尿病(T2 DM)减少(n=14~10)。JOT患者的2小时血糖(161 mg/dl~135 mg/dl)和30分钟胰岛素(42.8μU/ml~48.0μU/ml)有显著差异。2型糖尿病患者在稳态模型评分(HOMA-IR)(2.3~L4)、30min血糖(265 mg/dl~223 mg/dl)和2 h血糖(253 mg/dl~189 mg/dl)方面也有显著差异。

项目成果

メタボリックシンドロームおよびその予備軍を対象にした健康教育介入における肥満改善指標の検討

代谢综合征及代谢综合征高危人群健康教育干预中肥胖改善指数的考察

• 发表时间: 2008
• 期刊: 日本農村医学会雑誌 56(6)
• 作者: 李麗梅;池西瑠美;岩本麻実子;乃木章子;山崎雅之;王莉;米山敏美;塩飽邦憲
• 通讯作者: 塩飽邦憲

Lifestyle and obesity-related metabolic disorders in Northeast Asia

东北亚的生活方式和与肥胖相关的代谢紊乱

• 发表时间: 2006
• 作者: Shiwaku K;Nogi A;Watanabe M;Yamasaki M;Yoneyama T
• 通讯作者: Yoneyama T

メタボリックシンドロームの疾病概念とその対策

代谢综合征的疾病概念及对策

• 发表时间: 2007
• 期刊: 日本農村医学会雑誌 56(4)
• 作者: 塩飽邦憲;山崎雅之;岩本麻実子;池西瑠美;米山敏美;李麗梅;王莉;乃木章子
• 通讯作者: 乃木章子

Predictive values of anthropometric measurements for visceral obesity and metabolic syndrome in educational intervention(発表予定)

人体测量对内脏肥胖和代谢综合征在教育干预中的预测价值（待发表）

• 发表时间: 2008
• 作者: Shiwaku K;Yamasaki M;Watanabe M;Nogi A;et. al.
• 通讯作者: et. al.

Predictive values of anthropometric measurements for visceral obesity and metabolic syndrome in educational intervention(In Japanese)

人体测量对内脏肥胖和代谢综合征在教育干预中的预测价值（日文）

• 发表时间: 2008
• 期刊: J JPN Assoc Rural Med 56
• 作者: Limei;LI;Rumi;IKENISHI;Mamiko;IWAMOTO;Akiko;NOGI;Masayuki;YAMASAKI;Li;WANG;Toshimi;YONEYAMA;Kuninori;SHIWAKU
• 通讯作者: SHIWAKU