Host iNOS dictates gut dysbiosis, bacterial translocation and tissue insulin resistance in murine and human obesity
Host iNOS dictates gut dysbiosis, bacterial translocation and tissue insulin resistance in murine and human obesity
批准号:
453491
负责人:
Marette Andr
金额:
$59.35万
依托单位:
依托单位国家:
加拿大
项目类别:
Operating Grants
财政年份:
2021
资助国家:
加拿大
项目状态:
未结题
起止时间:
2021-09-01 至 2026-09-01
中文摘要
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英文摘要
Changes in the type of gut microbes (known of the microbiota) can promote obesity and diabetes. We showed that type 2 diabetes alters bacteria in adipose tissues and the liver in obese persons and we now propose that alterations in the immune system and h
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