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Effects of vegetable consumption on postprandial glucose and lipid metabolism including serum adipocytokine

蔬菜消费对餐后糖脂代谢（包括血清脂肪细胞因子）的影响

基本信息

批准号：
18300257
负责人：
MARUYAMA Chizuko
金额：
$ 10.46万
依托单位：
Japan Women's University
依托单位国家：
日本
项目类别：
Grant-in-Aid for Scientific Research (B)
财政年份：
2006
资助国家：
日本
起止时间：
2006 至 2007
项目状态：
已结题

项目摘要

Healthy subjects and subjects with obese and hypertriglyceridemia consumed three test meals ; bread (B) meal, bread and butter (BB) meal, bread and butter with spinach(BBS) meal. Blood were collected at fasting, 30, 60, 120, 180 and 240 minutes after each test meal consumption.Results : In the healthy subjects, postprandial glucose levels tended to be lower and triglyceride levels were significantly higher after BB meal compared to after B meal. Plasma glucose level at 30 minutes after BBS meal was lower than that of after B meal (p<0.05). In the subjects with obese and hypertriglyceridemia, postprandial triglyceride levels were higher after BB meal compared to after B meal, and plasma glucose level at 30 minutes after BBS meal was lower than that of after B and BB meal. Plasma homocystein concentration was lower after BBS meal compared to after BB meal. Postprandial pre-heparin lipoprotein lipase mass did not differ between the BB and BBS meal. TNF-alpha concentration tended to decrea … More se after BB meal, however, those tended to decrease at 30 minutes and increased to the fasting level after BBS meal. From these results, butter consumption with bread might contribute to suppress postprandial hyperglycemia, but cause hypertriglyceridemia. In the healthy subjects, spinach consumption with bread and butter suggested to have possibility to protect postprandial hyperglycemia.Study 2.Subjects were recruited among trading company employee who were indicated to get nutrition education concerning metabolic syndrome. The subjects were allocated to Control group who were educated as usual, and to Veg group who were emphasized to encourage consuming more vegetables compared to usual advice. Blood was obtained at baseline and 3 month after intervention. Result : Significant change in body weight was observed in the Veg group with 3.6kg decrease more than 1.1kg in the Control group (p<0.05). Vegetable intake increased about 50 g in the Veg group and decreased about 150g in the Control group. Nutrition education emphasized to increase vegetable intake are suggested to be effective for body weight reduction. Less

健康受试者和肥胖及高甘油三酯血症受试者食用三顿测试餐；面包（B）餐、面包黄油（BB）餐、面包黄油菠菜（BBS）餐。空腹、每次测试餐后30、60、120、180和240分钟采血。结果：在健康受试者中，与B餐后相比，BB餐后餐后血糖水平往往较低，甘油三酯水平显着升高。 BBS餐后30分钟的血浆葡萄糖水平低于B餐后的血浆葡萄糖水平(p<0.05)。在肥胖和高甘油三酯血症受试者中，BB餐后的餐后甘油三酯水平较B餐后更高，且BBS餐后30分钟的血糖水平低于B餐后和BB餐后。与 BB 餐后相比，BBS 餐后血浆同型半胱氨酸浓度较低。 BB 餐和 BBS 餐之间的餐后肝素前脂蛋白脂肪酶质量没有差异。 BB餐后TNF-α浓度趋于下降，但在30分钟时趋于下降，并在BBS餐后增加至空腹水平。从这些结果来看，与面包一起食用黄油可能有助于抑制餐后高血糖，但会导致高甘油三酯血症。在健康受试者中，菠菜与面包和黄油一起食用有可能预防餐后高血糖。研究2.受试者是在贸易公司员工中招募的，他们被要求接受有关代谢综合征的营养教育。受试者被分配到对照组，他们像往常一样接受教育，而蔬菜组则被强调鼓励比通常的建议多吃蔬菜。在基线和干预后 3 个月采集血液。结果：素食组的体重发生了显着变化，比对照组减少了 3.6 公斤（p<0.05）。蔬菜组的蔬菜摄入量增加了约 50 克，对照组的蔬菜摄入量减少了约 150 克。建议强调增加蔬菜摄入量的营养教育对减肥有效。较少的