Mechanisms underlying circulation of selenium in Biosphere
Mechanisms underlying circulation of selenium in Biosphere
批准号:
19390033
负责人:
OGRA Yasumitsu
金额:
$10.9万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009
中文摘要
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英文摘要
Selenium (Se) shows ambivalent characteristics in animals and plants. It is an essential element in animals but becomes severely toxic when the amount ingested exceeds the required level. Meanwhile, Se is not essential in plants although some plants are Se hyperaccumulators. Thus, Se may be circulated in biosphere. In the study, we obtained the results for the mechanisms underlying the Se metabolism in animals and plants, the distinguish between Se and tellurium in animals and plants, the novel approach for metal/metalloid metabolism by the combination techniques of molecular biology, speciation and elemental imaging as shown below.
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Copper accumulation and compartmentalization in mouse fibroblast lacking metallothionein and copper chaperone, Atoxl
缺乏金属硫蛋白和铜伴侣 Atoxl 的小鼠成纤维细胞中的铜积累和区室化
DOI:
--
发表时间:
2009
期刊:
237
影响因子:
--
作者:
[T.Miyayama, K.T.Suzuki, Y.Ogra]
通讯作者:
Y.Ogra
メタロミクスにおけるナノスペシエーション
金属组学中的纳米形态
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[小椋康光]
通讯作者:
小椋康光
in vitro translation法を用いたセレノアミノ酸の取り込みとセレン含有タンパク質の構造及び酵素活性に与える影響
体外翻译法掺入硒氨基酸及其对含硒蛋白结构和酶活性的影响
DOI:
--
发表时间:
2007
期刊:
影响因子:
--
作者:
[則竹 瞬・中村修一・柴田哲男・融健, 北口 隆]
通讯作者:
北口 隆
Toxicometallomics for research on toxicology of exotic metalloids based on speciation studies.
毒物金属组学,用于基于形态研究的外来非金属毒理学研究。
DOI:
--
发表时间:
2009
期刊:
Anal. Sci. 25
影响因子:
--
作者:
[小沢政成, 本間雅, 徳田篤志, 鈴木洋史, Y. Ogra*]
通讯作者:
Y. Ogra*
DOI:
10.1016/j.taap.2009.05.006
发表时间:
2009-07-15
期刊:
TOXICOLOGY AND APPLIED PHARMACOLOGY
影响因子:
3.8
作者:
[Naranmandura, Hua, Ogra, Yasumitsu, Le, X. Chris]
通讯作者:
Le, X. Chris
共 65 条
Mechanism underlying the generation of reactive cyanogen species
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批准号:18K19387
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项目类别:Grant-in-Aid for Challenging Research (Exploratory)
-
资助金额:$4.08万
-
财政年份:2018
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负责人:OGRA Yasumitsu
-
依托单位:
Development of novel on-site analysis of urinary selenometabolites
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批准号:24659022
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.41万
-
财政年份:2012
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负责人:OGRA Yasumitsu
-
依托单位:
Elucidation of Selenium Metabolism in mammalian cells by speciation
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批准号:23390032
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.82万
-
财政年份:2011
-
负责人:OGRA Yasumitsu
-
依托单位:
海外基金