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The basic study of the effect of biocompatible phospholipid polymer on the osteoarthritis progression

The basic study of the effect of biocompatible phospholipid polymer on the osteoarthritis progression
生物相容性磷脂聚合物对骨关节炎进展影响的基础研究
批准号:
19390388
负责人:
MORO Toru
金额:
$11.48万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2009

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中文摘要
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英文摘要
To evaluate the effect of biocompatible phospholipid polymer on the osteoarthritis progression, we used the ball-on-flat machine, which mimicked a natural joint, and the experimental osteoarthritis model. The friction tests using a ball-on-flat machine revealed that phospholipid polymer extremely improved the friction coefficient as compared to water and hyaluronic acid treatment. In addition, phospholipid polymer prevented the osteoarthritis progression in the experimental osteoarthritis model. From these results of the study, we believe that this new technology will prevent the osteoarthritis progression.
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Enhanced wear resistance of orthopaedic bearing due to the cross-linking of poly (MPC) graft chains induced by gamma-rayirradiation
伽玛射线辐照诱导的聚 (MPC) 接枝链交联增强了骨科轴承的耐磨性
DOI: --
发表时间: 2008
期刊: J Biomed Mater Res B 84
影响因子: --
作者: [Masayuki Kyomoto, et. al.]
通讯作者: et. al.
Phosphorylation of, GSK-3p by cGMP-dependent protein kinase II promotes hypertrophic differentiation of murine chondrocytes.
cGMP 依赖性蛋白激酶 II 磷酸化 GSK-3p 可促进小鼠软骨细胞的肥大分化。
DOI: --
发表时间: 2008
期刊: J Clin Invest 118
影响因子: --
作者: [Kawasaki Y, et al]
通讯作者: et al
Antithrombogenic Polymer Alloy with Well-defined Block-type Phospholipid Polymer and Segmented Polyurethane for Cardiovascular Medical Devices
用于心血管医疗器械的具有明确嵌段型磷脂聚合物和嵌段聚氨酯的抗血栓聚合物合金
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [Ishihara K, Matsuno R, Konno T, Takai M, Asanuma Y]
通讯作者: Asanuma Y
変形性関節症の診断と治療 : 最近の進歩
骨关节炎的诊断和治疗:最新进展
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [Miyake J, Murase T, Moritomo H, 荒木令江, Hirata M, Moritomo H, 川口浩]
通讯作者: 川口浩
129
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    • 批准号:
      23390359
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $11.4万
    • 财政年份:
      2011
    • 负责人:
      MORO Toru
    • 依托单位:
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    • 批准号:
      17591548
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.18万
    • 财政年份:
      2005
    • 负责人:
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    • 依托单位:
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