Establishments of early screening of visual cognitive impairment and application to the rehabilitation.

视觉认知障碍早期筛查的建立及其在康复中的应用

• 批准号: 19500457
• 负责人: GOTO Yoshinobu
• 金额: $ 2.91万
• 依托单位: International University of Health and Welfare
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2007
• 资助国家: 日本
• 起止时间: 2007 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19500457/
• 关键词: 視空間認知障害; 運動視; 脳神経機能障害; 事象関連電位; 探索眼球運動; 放射状運動(optic flow); 軽度認知障害; リハビリテーション; 視覚情報処理

It is well known that the higher-level dorsal stream integrates local motion signals from V1 into global motion. Thus, coherent motion stimuli will be able to use for evaluating the global motion defects. In addition, there are several types of global motion including radial optic flow (OF) and horizontal motion (HO). In this study, ERPs elicited by coherent OF and HO stimuli were recorded and analyzed in healthy young and old adults, and mild cognitive impairment patients. In the results, two major components (N170 and P200) were obtained in healthy young adults. N170 with V5/MT origin was evoked by both stimuli. In contrast, P200 with an IPL (BA 40) origin was elicited only by OF. These findings suggested that N170 was a nonspecific motion-related component originating from V5/MT, while P200 was an OF-specific component generated by the IPL. Therefore, a combined approach of ERPs using coherent motion (particularly OF) can be useful for discriminating MCI and AD patients from healthy old adults.

众所周知，较高水平的背侧流将来自V1的局部运动信号整合为全局运动。因此，相干运动刺激将能够用于评估全局运动缺陷。此外，还有几种类型的全球运动，包括径向光流(OF)和水平运动(HO)。在这项研究中，记录和分析了健康的年轻人和老年人以及轻度认知障碍患者的相干OF和HO刺激诱发的事件相关电位。在结果中，在健康的年轻人中获得了两个主要成分(N170和P200)。两种刺激均可诱发V5/MT起源的N170。相反，起源于IPL(BA 40)的P200仅由Of诱导。这些发现表明，N170是起源于V5/MT的非特异性运动相关成分，而P200是由IPL产生的OF特异性成分。因此，结合连贯运动的ERPs方法(尤其是OF)有助于将MCI和AD患者与健康老年人区分开来。

项目成果

視覚誘発電位(VEP):基礎.

视觉诱发电位 (VEP)：基础知识。

• 发表时间: 2008
• 期刊: 臨床神経生理学 36(4
• 作者: 後藤純信;飛松省三
• 通讯作者: 飛松省三

Different perceptual sensitivities for Chernoff's face between children and adults.

儿童和成人对切尔诺夫脸的感知敏感度不同。

• 发表时间: 2008
• 期刊: Neuroscience Research 60(2)
• 作者: 加藤倫子;橋本修治;簗瀬正伸;小田登,真野暁子;橋村一彦;植田初江;駒村和雄,北村惣一郎;中谷武嗣;Tsurusawa R
• 通讯作者: Tsurusawa R

Changes in visual evoked magnetic fi elds during mental arithmetic task.

心算任务期间视觉诱发磁场的变化。

• 发表时间: 2009
• 作者: Mizuno K;Okamoto T;Ikeda T;Goto Y
• 通讯作者: Goto Y

Exploratory eye movements in psychiatric diseases

精神疾病中的探索性眼球运动

• 发表时间: 2009
• 作者: 植木純;笠木聡;十合晋作;Goto Y
• 通讯作者: Goto Y

Feasibility of exploratory eye movements in patients with neurological and psychiatric diseases.

神经和精神疾病患者探索性眼球运动的可行性。

• 发表时间: 2009
• 期刊: 2009 IEEE (CME2009) International Conference on Complex Medical Engineering 有
• 作者: Goto Y;Yoshida T;Hayasaka T;Nakayama H
• 通讯作者: Nakayama H