Immunostimulating effects of health foods on murine macrophage cell line

采用小鼠巨噬细胞系研究了各种保健食品的免疫刺激作用。将这些食物添加到细胞系的培养基中，并在显微镜下观察细胞的形态变化，作为效果的指标。结果表明，在检测的保健食品中，蘑菇和香菇菌丝体提取物（LEM）具有免疫刺激作用。然后，检测了这些食品的抗单核细胞增生李斯特菌活性。经真菌处理的细胞抗李斯特菌活性明显高于未经真菌处理的细胞，这可能与活性氧依赖有关。

Immunostimulating effects of various health foods were studied using murine macrophage cell line. These foods were added to the culture medium of the cell line, and, as an index of the effects, morphological changes of the cell were searched under the microscope. As a result, among the health foods tested, immunostimulating effects could be expected in agaricus and extracts from Lentinula edodes mycelia (LEM). Next, anti-Listeria monocytogenes activities of these foods were examined. The agaricus-treated cells had increased anti-Listeria activity than the non-treated cells, which was suggested to derive from active oxygen dependence.