Control of Wolbachia replication: maintaining a stable symbiosis

该项目将使用比较基因组学方法来更好地了解昆虫的沃尔巴克氏体感染如何能够在昆虫中维持自身而不引起病理学。这些结果将使我们更好地理解细胞内共生体的一个显著特征，即复制控制。这些结果也有可能通过更好地了解沃尔巴克氏体如何被用来扭曲昆虫种群年龄结构，从而导致新的方法来控制昆虫害虫。

This project will use a comparative genomics approach to better understand how Wolbachia infections of insects are able to maintain themselves in insects without causing pathology. The results will allow us to better understand a distinguishing characteristic of an intracellular symbiont, namely replication control. The results also have the potential to lead to new approaches to insect pest control through a better understanding of how Wolbachia might be used to skew insect population age structure.