Preparation of environmental materials consisting of salmon milt DNA

鲑鱼鱼白DNA环保材料的制备

• 批准号: 19750187
• 负责人: YAMADA Masanori
• 金额: $ 2.37万
• 依托单位: Okayama University of Science
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Young Scientists (B)
• 财政年份: 2007
• 资助国家: 日本
• 起止时间: 2007 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19750187/
• 关键词: DNA; 環境浄化剤; 生体高分子; 内分泌かく乱化学物質; インターカレーション; 二重らせん; ダイオキシン; 環境調和型材料; 環境浄化材

Recently, we prepared water-insoluble DNA-films by UV irradiation. These DNA-films bound endocrine disruptors having a planar structure, such as dioxin and PCB derivatives. However, other harmful endocrine disruptors, which lack a planar structure, such as bisphenol A and diethylstilbestrol, did not bind to the water-insoluble DNA-films. Therefore, we prepared the DNA.cyclodextrin composite material by mixing the DNA and the cyclodextrin (CD). As a result, these composite materials had properties of both the double-stranded DNA, such as intercalation, and the CD, such as encapsulation of an organic molecule into the intramolecular cavity. Therefore, these materials could accumulate not only the harmful compounds with a planar structure, but also the non-planar molecules, such as bisphenol A and diethylstilbestrol. These DNA-CD composite materials may have the potential as novel environmental materials that absorb harmful compounds.

最近，我们通过紫外照射制备了水不溶性DNA膜。这些DNA膜结合具有平面结构的内分泌干扰物，如二恶英和PCB衍生物。然而，其他有害的内分泌干扰物，缺乏平面结构，如双酚A和己烯雌酚，没有结合到水不溶性DNA膜。因此，我们将DNA与环糊精（CD）混合，制备了DNA-CD复合材料。结果，这些复合材料具有双链DNA的性质，例如嵌入，和CD，例如将有机分子封装到分子内空腔中。因此，这些材料不仅可以积累具有平面结构的有害化合物，而且还可以积累非平面分子，例如双酚A和己烯雌酚。这些DNA-CD复合材料可能具有作为吸收有害化合物的新型环境材料的潜力。

项目成果

DNA-シクロデキストリン複合体を用いた有害物質の選択的除去

利用 DNA-环糊精复合物选择性去除有害物质

• 发表时间: 2009
• 作者: 田淵慎也;山田真路
• 通讯作者: 山田真路

DNAや生体高分子を含んだ機能性材料の創生

创建含有 DNA 和生物聚合物的功能材料

• 发表时间: 2007
• 作者: 天羽生 真梨子;杉山 太郎;山田真路
• 通讯作者: 山田真路

Molecular structure of chlorocycloheptane in inclusion compound with 9,9'-bianthryl and gelation during crystallization

9,9-联蒽包合物中氯环庚烷的分子结构及结晶过程中的凝胶化

• 发表时间: 2008
• 期刊: Bull. Chem. Soc. Jpn 82
• 作者: S. Toyota;Y. Okamoto;T. Ishikawa;T. Iwanaga;and M. Yamada
• 通讯作者: and M. Yamada

Bio-inspired membranes for advanced polymer electrolyte fuel cell

用于先进聚合物电解质燃料电池的仿生膜

• 发表时间: 2007
• 期刊: Bull. Chem. Soc. Jpn. 80
• 作者: I. Honma;M. Yamada
• 通讯作者: M. Yamada

DNA–inorganic hybrid material as selective absorbent for harmful compounds

• DOI: 10.1016/j.polymer.2008.08.027
• 发表时间: 2008-10
• 期刊: Polymer
• 影响因子: 4.6
• 作者: M. Yamada;Hirofumi Aono