Preparation of environmental materials consisting of salmon milt DNA

点击翻译按钮获取中文摘要

Recently, we prepared water-insoluble DNA-films by UV irradiation. These DNA-films bound endocrine disruptors having a planar structure, such as dioxin and PCB derivatives. However, other harmful endocrine disruptors, which lack a planar structure, such as bisphenol A and diethylstilbestrol, did not bind to the water-insoluble DNA-films. Therefore, we prepared the DNA.cyclodextrin composite material by mixing the DNA and the cyclodextrin (CD). As a result, these composite materials had properties of both the double-stranded DNA, such as intercalation, and the CD, such as encapsulation of an organic molecule into the intramolecular cavity. Therefore, these materials could accumulate not only the harmful compounds with a planar structure, but also the non-planar molecules, such as bisphenol A and diethylstilbestrol. These DNA-CD composite materials may have the potential as novel environmental materials that absorb harmful compounds.