Molecular basis of one-carbon metabolism of microorganisms and the regulatory mechanism of the gene expression
Molecular basis of one-carbon metabolism of microorganisms and the regulatory mechanism of the gene expression
批准号:
19780058
负责人:
YURIMOTO Hiroya
金额:
$2.41万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Young Scientists (B)
财政年份:
2007
资助国家:
日本
项目状态:
已结题
起止时间:
2007 至 2008
中文摘要
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英文摘要
酵母メタノール誘導性遺伝子発現に関わる転写因子を新たに取得し、Trm1 がメタノール特異的誘導、Trm2 がグルコース脱抑制に関わる転写因子として機能していることを明らかにした。枯草菌のホルムアルデヒド応答性遺伝子発現制御機構を利用し、ホルムアルデヒドを検出できるセンサー細胞を開発した。メタノール資化性細菌のホルムアルデヒド固定経路の酵素(HPS, PHI)を人工的に融合した二機能性酵素を創製し、ホルムアルデヒド資化性や耐性を異種生物に付与することに成功した。
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Trmlp, a Zn(II)2Cys6-type transcription factor, is a master regulator of methanol-specific gene activation in the methylotrophic yeast Candida boidinii
Tmlp 是一种 Zn(II)2Cys6 型转录因子,是甲基营养酵母 Candida boidinii 中甲醇特异性基因激活的主要调节因子
DOI:
--
发表时间:
2008
期刊:
Eukaryot. Cell. 7
影响因子:
--
作者:
[Sasano, Y., et. al.]
通讯作者:
et. al.
Gene-tagging mutagenesis in the methylotrophic yeast Candida boidinii
甲基营养酵母博伊丁假丝酵母的基因标记诱变
DOI:
--
发表时间:
2007
期刊:
J. Biosci. Bioeng. 104
影响因子:
--
作者:
[Sasano, Y., H. Yurimoto, Y. Sakai]
通讯作者:
Y. Sakai
Overexpression and purification of rat peroxisomal membrane protein 22, PMP22, in Pichia pastoris.
大鼠过氧化物酶体膜蛋白 22 (PMP22) 在毕赤酵母中的过表达和纯化。
DOI:
--
发表时间:
2009
期刊:
Protein Expression and Purification
影响因子:
1.6
作者:
[K. Egawa, H. Shibata, S. Yamashita, H. Yurimoto, Y. Sakai, H. Kato]
通讯作者:
H. Kato
DOI:
10.1007/s00253-007-1023-8
发表时间:
2007-08-01
期刊:
APPLIED MICROBIOLOGY AND BIOTECHNOLOGY
影响因子:
5
作者:
[Orita, Izumi, Sakamoto, Naoki, Sakai, Yasuyoshi]
通讯作者:
Sakai, Yasuyoshi
Development of the novel methanol bioconversion systems for a low-carbon and resource-recycling society and elucidation of their molecular basis
-
批准号:19H04326
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.23万
-
财政年份:2019
-
负责人:YURIMOTO Hiroya
-
依托单位:
Molecular mechanism of interactions between phyllosphere C1-microbes and plants and its application in environmental conservation agriculture
-
批准号:19K22307
-
项目类别:Grant-in-Aid for Challenging Research (Exploratory)
-
资助金额:$3.99万
-
财政年份:2019
-
负责人:YURIMOTO Hiroya
-
依托单位:
Production of functional RNA from methanol using high transcription potential of methylotrophic yeasts
-
批准号:16K15089
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.41万
-
财政年份:2016
-
负责人:YURIMOTO Hiroya
-
依托单位:
Methanol economy pioneered by C1-microorganisms: development of basic technologies utilized in low-carbon and sustainable society
-
批准号:16H02997
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$10.73万
-
财政年份:2016
-
负责人:YURIMOTO Hiroya
-
依托单位:
Development of novel metabolic engineering technology using one-carbon compounds and their metabolic regulatory systems
-
批准号:25660079
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.58万
-
财政年份:2013
-
负责人:YURIMOTO Hiroya
-
依托单位:
Molecular basis of metabolic physiology of C1-microorganisms and its application in methanol economy
-
批准号:25281063
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.56万
-
财政年份:2013
-
负责人:YURIMOTO Hiroya
-
依托单位:
Development of environmental technology based on molecular basis of microbial one-carbon metabolism
-
批准号:22310046
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$11.98万
-
财政年份:2010
-
负责人:YURIMOTO Hiroya
-
依托单位:
海外基金