Basic research of a novel dental material : Calcium Titanium Oxide-Amorphous Carbon for applying the lining material

新型牙科材料：钛酸钙-无定形碳内衬材料的基础研究

• 批准号: 19592236
• 负责人: TAKAGI Yoru
• 金额: $ 2.91万
• 依托单位: Okayama University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2007
• 资助国家: 日本
• 起止时间: 2007 至 2009
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-19592236/
• 关键词: 歯科材料; 生体材料; チタン酸カルシウム; ナノ粒子; 裏装材; 細胞反応; アルコキシド法; ライナー材; チタン; チタン酸; 細胞毒性; 非晶質炭素

We have developed modified thermal decomposition method to obtained "calcium titanium oxide-amorphous carbon" (CaTiO3-aC). The purpose of the research was to evaluate the effect of this material as nanoparticles for applying the dental material. We analyzed the chemical composition of the particles and studied it's influence on the cell. Our results suggest that CaTiO3-aC plays a dominant effect on cell response, which could be considered as an important biomaterial for not only dental materials but also medical and industrial materisls.

本文采用改进的热分解法制备了"钙钛氧化物-无定形碳"（CaTiO_3-aC）。本研究的目的是评估这种材料作为纳米颗粒应用于牙科材料的效果。我们分析了颗粒的化学成分，并研究了它对细胞的影响。结果表明，CaTiO_3-aC在细胞反应中起主导作用，不仅可用作牙科材料，而且可用作医用和工业材料。

项目成果

下顎歯肉腫瘍

下颌牙龈肿瘤

• 发表时间: 2007
• 作者: Tsujigiwa H;Nagatsuka H;Han PP;Gunduz M;Siar CH;Oida S and Nagai N;Shimizu T;Kawakami T;Inoue M;Tsujigiwa H;Nagatsuka H;Tsujigiwa H;Gul San Ara Sathi;Silvia Borkosky;Mahmoud Al Sheikh All;Lefeuvre Mathieu;Silvia Susana Borkosky;Gul San Ara Sathi;Mahmoud Al Sheikh Ali;M. Gunduz;R. Rivera;長塚仁;片瀬直樹;中野敬介;玉村亮;佐藤文彦;Beder Levent;Rivera RS;金田祥弘;胡海龍;井上美穂;森宏樹;Rodriguez Andrea Paola;辻極秀次;中野敬介;清水貴子;中野敬介;グンデゥズ メーメット;グンデゥズ エスラ;岡内美佳;清水貴子;玉村亮;片瀬直樹
• 通讯作者: 片瀬直樹

Downregulation of ING3 mRNA expression predicts poor prognosis in head and neck cancer

• DOI: 10.1111/j.1349-7006.2007.00708.x
• 发表时间: 2008-03-01
• 期刊: CANCER SCIENCE
• 影响因子: 5.7
• 作者: Gunduz, Mehmet;Beder, Levent Bekir;Nagai, Noriyuki
• 通讯作者: Nagai, Noriyuki

Characterization and Gene Expression Profiling of Human Mesenchymal Stem Cells

人类间充质干细胞的表征和基因表达谱

• 发表时间: 2007
• 期刊: J. Hard Tissue Biol. 16
• 作者: Hiroki Mori;Yoshitaro Itano;Naoya Kobayashi;Yoshikazu Kosaka;Noriaki Tanaka;Hitoshi Nagatsuka;Masahisa Inoues;Kojun Setsu;Tohru Nakanishi
• 通讯作者: Tohru Nakanishi

Analysis of the neoplastic nature and biological potential of sporadic and nevoid basal cell carcinoma syndrome-associated keratocystic odontogenic tumor

• DOI: 10.1111/j.1600-0714.2007.00578.x
• 发表时间: 2007-10-01
• 期刊: JOURNAL OF ORAL PATHOLOGY & MEDICINE
• 影响因子: 3.3
• 作者: Katase, Naoki;Nagatsuka, Hitoshi;Nagai, Noriyuki
• 通讯作者: Nagai, Noriyuki

C-kit protein expression correlated with activating mutations in KIT gene in oral mucosal melanoma

• DOI: 10.1007/s00428-007-0524-2
• 发表时间: 2008-01-01
• 期刊: VIRCHOWS ARCHIV
• 影响因子: 3.5
• 作者: Rivera, Rosario S.;Nagatsuka, Hitoshi;Nagai, Noriyuki
• 通讯作者: Nagai, Noriyuki