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Identification and a functional analysis of susceptibility genes of Eating Disorders by GWAS

Identification and a functional analysis of susceptibility genes of Eating Disorders by GWAS
饮食失调易感基因的全基因组关联分析(GWAS)
批准号:
20390201
负责人:
KOMAKI Gen
金额:
$11.9万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

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中文摘要
翻译
在本研究中,我们检测了在先前研究中已经在神经性厌食症患者样本的10个区域中检测到的微卫星标记物。结果发现,只有一个位点D1S0562i的等位基因和频率与前一个相同,这一发现满足Hardy-Weinberg平衡。最后,估计有两个单倍型的比值比高于单独的D1S0562i。
英文摘要
In the present study, we examined microsatellite markers that had been already detected in 10regions in Anorexia Nervosa patient samples in the previous study. As a result, only one locus, D1S0562i, was identified where the allele and frequency were identical to the previous one and this finding was satisfied with the Hardy-Weinberg Equilibrium. Finally, two haplotypes were estimated that are higher in odds ratio than that of D1S0562i alone.
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DOI: 10.1186/1471-2350-11-123
发表时间: 2010-08-11
期刊: BMC medical genetics
影响因子: --
作者: [Michikawa Y, Suga T, Ishikawa A, Hayashi H, Oka A, Inoko H, Iwakawa M, Imai T]
通讯作者: Imai T
DOI: 10.1186/1751-0759-3-12
发表时间: 2009-11-03
期刊: BioPsychoSocial medicine
影响因子: 2.1
作者: [Nishimura H, Komaki G, Igarashi T, Moriguchi Y, Kajiwara S, Akasaka T]
通讯作者: Akasaka T
小牧元:摂食障害簡略版&詳細版.みんなのメンタルヘルス総合サイト~こころの病気・精神障害の方の治療・生活を応援する総合サイト
Hajime Komaki:饮食失调简化版和详细版 每个人的心理健康综合网站〜支持精神疾病和精神障碍患者的治疗和生活方式的综合网站。
DOI: --
发表时间:
期刊:
影响因子: --
作者: []
通讯作者:
Role of ghrelin gene variants in eating disorders, and eating disorder-related characteristics of young Japanese women
生长素释放肽基因变异在饮食失调中的作用以及日本年轻女性饮食失调相关特征
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [Ando T, Komaki G, Ichimaru Y, Konjiki F, the Japanese Genetic Research Group For Eating Disorders]
通讯作者: the Japanese Genetic Research Group For Eating Disorders
59
    Large Epidemiological Study on Eating Disorders and Risk Factors of Junior High School Students: Compared with Five Years Ago
    Identification of susceptibility genes of Anorexia Nervosa by GWAS
    The analysis of molecular mechanisms of autoimmune thyroid diseases
    • 批准号:
      08671166
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $1.41万
    • 财政年份:
      1996
    • 负责人:
      KOMAKI Gen
    • 依托单位:
    海外基金