New therapeutic approach for glaucoma via drug-mediated bleb regulation
New therapeutic approach for glaucoma via drug-mediated bleb regulation
批准号:
20390449
负责人:
TANIHARA Hidenobu
金额:
$12.31万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
我们确定了小梁切除术手术失败的危险因素,小梁切除术是青光眼患者的主要手术。在开放性青光眼患者中,既往白内障手术是手术失败的重要危险因素,而在葡萄膜炎性青光眼患者中,既往白内障手术和肉芽肿性葡萄膜炎类型是危险因素。抗血管内皮生长因子药物贝伐单抗可减少手术并发症,并提高小梁切除术的短期手术成功率。
英文摘要
We identified risk factors for surgical failure of trabeculectomy, a major surgery for glaucoma patients. In open-glaucoma patients, previous cataract surgery is a significant risk factor for the surgical failure while previous cataract surgery and granulomatous uveitis-type are risk factors in uveitic glaucoma patients. An anti-VEGF drug, bevacizumab, reduces surgical complications, and improves the short-term surgical success of trabeculectomy.
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線維柱帯切除術の白内障手術が眼圧経過に与える影響の検討
白内障小梁切除术对眼压过程影响的探讨
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[笠岡奈々子, 井上俊洋, 川口淳, 瀧原祐史, 瀬戸孝彦, 稲谷大, 岩尾美奈子, 布田龍佑, 谷原秀信]
通讯作者:
谷原秀信
Intraocular Pressure Elevation After Intraocular Lens Suture Fixation for Ectopia of Crystalline or Intraocular Lenses.
晶体或人工晶状体异位人工晶状体缝合固定后眼压升高。
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Eiki D, Inatani M, Inoue T, Kasaoka N, Takihara Y, Tanihara H.]
通讯作者:
Tanihara H.
開放隅角緑内障に対するトラベクレクトミー単独手術と白内障同時手術との前向き比較研究
单纯小梁切除术与同时白内障手术治疗开角型青光眼的前瞻性比较研究
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[岩尾美奈子, 稲谷大, 瀧原祐史, 岩尾圭一郎, 井上俊洋, 笠岡奈々子, 谷原秀信]
通讯作者:
谷原秀信
DOI:
--
发表时间:
2008
期刊:
SNJ-1656, in normal volunteers. Archives of Ophthalmology 126
影响因子:
--
作者:
[Tanihara H, Inatani M, Honjo M, Tokushige H, Azuma J, Araie M]
通讯作者:
Araie M
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[岩尾圭一郎, 稲谷大]
通讯作者:
稲谷大
共 32 条
Study on development of new therapeutic methods based on plasticity of trabecular meshwork cells
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批准号:17K19729
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项目类别:Grant-in-Aid for Challenging Research (Exploratory)
-
资助金额:$4.08万
-
财政年份:2017
-
负责人:TANIHARA Hidenobu
-
依托单位:
Investigation of glaucoma pathology focusing on epigenome and fibrocyte in aqueous humor dynamics and wound healing
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批准号:17H04351
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.9万
-
财政年份:2017
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负责人:TANIHARA Hidenobu
-
依托单位:
4-dimention live imaging of inflamatory cells in conjunctiva after glaucoma surgery
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批准号:25670735
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.41万
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财政年份:2013
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负责人:TANIHARA Hidenobu
-
依托单位:
Establishment of therapeutic assessment in glaucoma neuroprotection using live-imaging of axonal transport in optic nerve
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批准号:23659814
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项目类别:Grant-in-Aid for Challenging Exploratory Research
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资助金额:$2.33万
-
财政年份:2011
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负责人:TANIHARA Hidenobu
-
依托单位:
The effects of aqueous bioactive molecules on aqueous outflow dynamics and filtration-surgery results
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批准号:23390403
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$11.98万
-
财政年份:2011
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负责人:TANIHARA Hidenobu
-
依托单位:
The investigation for molecular mechanisms of aqueous humor outflow and the creation of new treatments for intraocular pressure elevation in glaucomatous eyes
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批准号:18390470
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$10.59万
-
财政年份:2006
-
负责人:TANIHARA Hidenobu
-
依托单位:
The development and clinical application of molecular-based new medical treatments for glaucoma
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批准号:16390500
-
项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$9.22万
-
财政年份:2004
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负责人:TANIHARA Hidenobu
-
依托单位:
A research about the new therapy for glaucomatous optic nerve damage based on the endogenous neuroprotective system
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批准号:14370561
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$9.54万
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财政年份:2002
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负责人:TANIHARA Hidenobu
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依托单位:
Development of gene theropy for glaucoma by neaws of modulation of proteoglycan praduction in aqueous outflow rocite
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批准号:08457464
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项目类别:Grant-in-Aid for Scientific Research (B)
-
资助金额:$4.74万
-
财政年份:1996
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负责人:TANIHARA Hidenobu
-
依托单位:
海外基金