Field Study on natural medicinal resources in Bangladesh
Field Study on natural medicinal resources in Bangladesh
批准号:
20404004
负责人:
ISHIBASHI Masami
金额:
$8.07万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (B)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
2008-2011年,该研究项目的代表(Masami Ishibashi)每年访问孟加拉国,并对孟加拉国主要是热带植物的天然药用资源进行实地研究。结果,收集了近200种植物,主要是野外特有植物和当地栽培的药用植物。对这些植物材料的提取物进行了针对信号通路如Wnt、hedgehog和TRAIL的筛选试验,并从活性样品中分离出几种新的生物活性天然产物。
英文摘要
In 2008-2011 the representative of this research project (Masami Ishibashi) visited Bangladesh every year and investigated field-study on natural medicinal resources in Bangladesh mainly on tropical plants. As a result, approximately nearly 200 kinds of plant species were collected, and they were mainly field-characteristic plant species as well as locally cultivated medical herbs. Extracts of these plant materials were subjected to screening tests against signaling pathways such as Wnt, hedgehog, and TRAIL, and from active samples several new bioactive natural products were isolated.
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Hedgehog/GLI-mediated transcriptional inhibitors from Acacia pennata and Exocoecaria agallocha
来自 Acacia pennata 和 Exocoecaria agallocha 的 Hedgehog/GLI 介导的转录抑制剂
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[N.Mori, K.Toume, M.A.Arai, T.Koyano, T.Kowithayakorn, M.Ishibashi, Takeo Horie, M.A.Arai, 笹倉靖徳, M.A.Arai, 荒井緑, 笹倉靖徳, 荒井緑(代表)]
通讯作者:
荒井緑(代表)
神経幹細胞の分化促進作用をもつ天然物, 天然物様化合物の探索
寻找促进神经干细胞分化的天然产物和类天然产物化合物
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[N.Mori, K.Toume, M.A.Arai, T.Koyano, T.Kowithayakorn, M.Ishibashi, Takeo Horie, M.A.Arai, 笹倉靖徳, M.A.Arai, 荒井緑, 笹倉靖徳, 荒井緑(代表), 堀江健生, 荒井緑(代表)]
通讯作者:
荒井緑(代表)
Death receptor 5 promoter-enhancing compounds isolated from Catimbium speciosum and their enhancement effect on TRIL-induced apoptosis.
从 Catimbium spiosum 中分离出的死亡受体 5 启动子增强化合物及其对 TRIL 诱导的细胞凋亡的增强作用。
DOI:
--
发表时间:
2009
期刊:
Bioorganic Medicinal Chemistry 17
影响因子:
--
作者:
[五十嵐堅治, 眞子岳, 北脇秀敏, 中井泉, 小倉良太, S.K.Sadhu, 中井泉, T.Ohtsuki]
通讯作者:
T.Ohtsuki
Constituents of Pongamia pinnata isolatedin a screening for activity to overcome TRAIL-resistance
克服 TRAIL 抗性活性筛选中分离出的水黄皮成分
DOI:
--
发表时间:
2010
期刊:
Chem. Pharm. Bull
影响因子:
--
作者:
[Minakawa, T., Toume, K., Ahmed, F., Sadhu, S. K., Ohtsuki, T., Arai, M. A., Ishibashi, M.]
通讯作者:
M.
Vitex negundoからのヘッジホッグ伝達経路阻害剤の探索
从荆条中寻找刺猬传播途径抑制剂
DOI:
--
发表时间:
2011
期刊:
影响因子:
--
作者:
[荒井緑, 藤松輝久, A. K. Paul, F. Ahemd, S. K. Sadhu, 石橋正己]
通讯作者:
石橋正己
共 64 条
Screening study on natural products having effects on histone modification and epigenetic control mechanism
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批准号:25670045
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项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.5万
-
财政年份:2013
-
负责人:ISHIBASHI Masami
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依托单位:
Field Study on natural medicinal resources in Bangladesh
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批准号:23404007
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$10.98万
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财政年份:2011
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负责人:ISHIBASHI Masami
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依托单位:
Creation of small molecular resources with high function based on comprehensive natural products chemistry
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批准号:22310133
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.73万
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财政年份:2010
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负责人:ISHIBASHI Masami
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依托单位:
Comprehensive natural products study for development of small molecules targeting signaling pathways
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批准号:19310136
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$12.06万
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财政年份:2007
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负责人:ISHIBASHI Masami
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依托单位:
Search for Bioactive Natural Products from Unexplored Medicinal Resources
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批准号:14370716
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项目类别:Grant-in-Aid for Scientific Research (B)
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资助金额:$7.3万
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财政年份:2002
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负责人:ISHIBASHI Masami
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依托单位:
Studies on the stereochemistry of new macrolides from marine organisms for research and development of drug molecules
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批准号:07558208
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项目类别:Grant-in-Aid for Scientific Research (A)
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资助金额:$2.05万
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财政年份:1995
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负责人:ISHIBASHI Masami
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依托单位:
海外基金