Study on intra-species diversity of Giardia intestinalis : How has the diversity been maintained?

为了揭示肠道贾第虫不同基因型形成的驱动力，建立利用背景机制控制寄生虫的干预方法，我们在印度尼西亚松巴岛进行了一系列横断面分子流行病学调查。在本研究中，我们确认了该地点多种肠道原生动物寄生虫的地方性，并收集了多种原生动物标本作为遗传分析参考。根据不同的基因型，肠螟似乎具有不同的传播途径，这可能是由于生境隔离而保持了每种基因型的多样性。

)To Reveal the driving force behind the formation of various genotypes in the population of Giardia intestinalis, and to establish a novel intervention approach using the background mechanisms to control parasites, we conducted a series of cross-sectional molecular epidemiologic investigation in Sumba Island, Indonesia. In this study, we confirmed the endemic status of various intestinal protozoan parasites in the site, and collected various protozoan specimens as references for genetic analyses. G. intestinalis seems to possess different transmission routes according to the genotypes, which might be maintaining each diversified genotype as a result of habitat isolation.