Assessment of Cardiovascular Function in Metabolic Syndrome using Doppler Ultrasonography

通过分析代谢综合征患者的超声心动图表现，阐明代谢综合征患者的心脏结构和功能。相对室壁厚度、左室质量指数和左室射血分数在两组之间无差异。而二尖瓣血流E/A值在代谢综合征组与非代谢综合征组之间有显著性差异。代谢综合征患者即使没有左室肥厚或收缩功能障碍，也表现出左室舒张功能障碍。此外，我们阐明了左室功能的高血压（HT）和糖尿病（DM）患者在不同年龄层。组织多普勒超声心动图（TDE）评估的应变和应变率在HT组和DM组显示出低于健康对照组的值在每个年龄层。此外，HT+DM组的应变和应变率在各年龄层的所有四个组中显示最低值。虽然HT或DM影响正常的年龄相关的左室功能变化，但HT和DM共存比单独HT或DM对正常的年龄相关的变化有更有害的影响。

We elucidated the cardiac structure and function of patients with metabolic syndrome by analyzing echocardiographic findings in patients with metabolic syndrome. The relative wall thickness, LV mass index, and LV ejection fraction demonstrated no difference between the two groups. However, the ratio of E to A (E/A) of transmitral flow demonstrated significant difference between the metabolic syndrome and the non-metabolic syndrome groups. Patients with metabolic syndrome demonstrated LV diastolic dysfunction even if they have neither LV hypertrophy nor systolic dysfunction. Moreover, we elucidated the LV function in patients with hypertension (HT) and diabetes (DM) in various age strata. The strain and strain rate assessed by tissue Doppler echocardiography (TDE) in the HT group and DM group showed lower values than those in the healthy control subjects in each age stratum. Furthermore, the strain and strain rate in the HT+DM group showed the lowest values among all four groups in each age stratum. Although HT or DM affected normal age-related changes in LV function, the coexistence of HT and DM had a more harmful effect on the normal age-related changes than HT alone or DM alone.