Development of novel sulfur-atom donating agents intended to thiiranate alkenes

利用硫原子上取代基的吸电子特性和离去基团的能力，可以从无机或有机硫化合物中合成硫原子供体试剂。考察了它们的硫化能力，发现一些试剂能使硫杂环戊二烯类化合物保持构型。以人工甜味剂糖精为原料合成的硫化剂，在温和的反应条件下，可使富电子芳香杂环化合物苯并噻吩硫化。

Sulfur-atom donating reagents taking advantage of both the electron withdrawing character and the leaving group ability of the substituents bonding directly with the sulfur atom were easily synthesized from inorganic or organic sulfur compounds. As a result of investigating their sulfuration ability, some reagents were found to thiiranate alkenes with retention of configuration. The reagent synthesized from artificial sweetener saccharin was able to sulfurate benzothiophene, one of the electron-rich heteroaromatic compo unds, under mild reaction conditions.