Interaction between Potyvirus viral protein linked to the genome and host cell protein
Interaction between Potyvirus viral protein linked to the genome and host cell protein
批准号:
20580048
负责人:
MIYOSHI Hiroshi
金额:
$3.08万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
To investigate the binding specificity of TuMV VPg with eIF4E, we evaluated the kinetic parameters for the interactions of human eIF4E, C. elegans IFE-3 and IFE-5 and Arabidopsis eIFiso4E, by SPR. The results suggested that in cap-bound eIF4E orthologues, the VPg binds to the C-terminal region, which constitutes one side of the entrance to the cap-binding pocket, whereas in the cap-free state, VPg binds to the widely opened cap-binding pocket and its surrounding region.
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DOI:
10.1016/j.biochi.2008.03.013
发表时间:
2008-10-01
期刊:
BIOCHIMIE
影响因子:
3.9
作者:
[Miyoshi, Hiroshi, Okade, Hayato, Natsuaki, Tomohide]
通讯作者:
Natsuaki, Tomohide
Sertraline inhibits dynamin-dependent endocytosis by suppressing dynamin GTPase activities.
舍曲林通过抑制动力 GTP 酶活性来抑制动力依赖性内吞作用。
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Kiyofumi Takahashi, et al]
通讯作者:
et al
Specific transgene expression in virus-infected cells by virus protease cleavable transcription suppressor
病毒蛋白酶可裂解转录抑制因子在病毒感染细胞中的特异性转基因表达
DOI:
--
发表时间:
2009
期刊:
影响因子:
--
作者:
[Daisuke Asai, et al.]
通讯作者:
et al.
Suppression of dynamin GTPase activity by sertraline inhibits dynamin-dependent endocytosis
舍曲林抑制动力 GTP 酶活性可抑制动力依赖性内吞作用
DOI:
--
发表时间:
2010
期刊:
影响因子:
--
作者:
[Takahashi, K.]
通讯作者:
K.
Turnip mosaic virus genome-linked protein VPg binds C-terminal region of cap-bound initiation factor 4E ortholog without exhibiting host cellular specificity
芜菁花叶病毒基因组连锁蛋白 VPg 结合帽结合起始因子 4E 直向同源物的 C 末端区域,但不表现出宿主细胞特异性
DOI:
--
发表时间:
2009
期刊:
J.Biochem. Vol.145
影响因子:
--
作者:
[Okade H., Fujita Y., Miyamoto S., Tomoo K., Muto S., Miyoshi H., Natsuaki T., Rhoads RE., Ishida T.]
通讯作者:
Ishida T.
共 11 条
Development of the virus vaccine by the elucidation of the virulence of a plant virus
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批准号:23658042
-
项目类别:Grant-in-Aid for Challenging Exploratory Research
-
资助金额:$2.41万
-
财政年份:2011
-
负责人:MIYOSHI Hiroshi
-
依托单位:
Studies on roles of potyviral protein on plant viral disease
-
批准号:18580045
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.49万
-
财政年份:2006
-
负责人:MIYOSHI Hiroshi
-
依托单位:
Studies on interaction between potyvirus VPg and plant eIF(iso)4E
-
批准号:16580031
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.37万
-
财政年份:2004
-
负责人:MIYOSHI Hiroshi
-
依托单位:
Molecular studies on P2 and TRP channels to regulate uterine contractions
-
批准号:16591662
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.24万
-
财政年份:2004
-
负责人:MIYOSHI Hiroshi
-
依托单位:
Studies on ATP receptor and K ATP channel to regulate uterine contractility for tocolysis
-
批准号:14571564
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.24万
-
财政年份:2002
-
负责人:MIYOSHI Hiroshi
-
依托单位:
国内基金
海外基金
过氧化物酶体増殖物激活受体γ(PPARG)基因Y95C错义突变的致病作用与机理研究
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批准号:--
-
项目类别:--
-
资助金额:24万元
-
批准年份:2020
-
负责人:龚思倩
-
依托单位:
过氧化物酶体増殖物激活受体γ(PPARG)基因Y95C错义突变的致病作用与机理研究
-
批准号:82000759
-
项目类别:青年科学基金项目(C类)
-
资助金额:24.0万元
-
批准年份:2020
-
负责人:龚思倩
-
依托单位: