课题基金 / 基金详情

Analyses of DNA methylation and histone methylation changes in human malignancies

Analyses of DNA methylation and histone methylation changes in human malignancies
人类恶性肿瘤中 DNA 甲基化和组蛋白甲基化变化分析
批准号:
20590325
负责人:
KONDO Yutaka
金额:
$2.33万
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2009

项目摘要

项目成果

KONDO Yutaka的其他基金

相似基金

相关文献

中文摘要
翻译
点击翻译按钮获取中文摘要
英文摘要
In the current study, to clarify the contribution of epigenetic abnormalities to the human tumorigenesis, we conducted high-throughput analysis of DNA methylation, lysine 27 trimethylation and genetic alterations in human malignancies. Using malignant mesothelioma as a model, we demonstrated a characteristic epigenetic profile of human mesothelioma and uncover multiple distinct epigenetic abnormalities that lead to the silencing of tumor-suppressor genes in mesothelioma and could serve as diagnostic or prognostic targets.
期刊论文(0)
专著(0)
科研奖励(0)
会议论文
DOI: 10.1016/j.canlet.2009.04.020
发表时间: 2009-10-18
期刊: CANCER LETTERS
影响因子: 9.7
作者: [Yuki, Kanako, Natsume, Atsushi, Wakabayashi, Toshihiko]
通讯作者: Wakabayashi, Toshihiko
「At the Front of Epigenetic Research」Cross-talk of DNA methylation and histone methylation in human cancers.
“表观遗传学研究的前沿”人类癌症中 DNA 甲基化和组蛋白甲基化的交叉对话。
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [Kondo Y]
通讯作者: Kondo Y
Yonsei Medical Journal 「Epigenetic cross-talk between DNA methylation anc histone modifications in human cancers」
延世医学杂志“人类癌症中 DNA 甲基化和组蛋白修饰之间的表观遗传串扰”
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [Suzuki H, Toyota M, Kondo Y, Shinomura Y. Humana Press, Kondo Y., 岡本泰幸, Yutaka Kondo]
通讯作者: Yutaka Kondo
DOI: 10.1093/carcin/bgn170
发表时间: 2008-10-01
期刊: CARCINOGENESIS
影响因子: 4.7
作者: [Gao, Wentao, Kondo, Yutaka, Sekido, Yoshitaka]
通讯作者: Sekido, Yoshitaka
36
    Study of regulatory mechanism controlling cancer cell reprogramming
    Integrated studies of aerosol-cloud-precipitation system in Asia based on measurement and model calculations
    • 批准号:
      23221001
    • 项目类别:
      Grant-in-Aid for Scientific Research (S)
    • 资助金额:
      $137.7万
    • 财政年份:
      2011
    • 负责人:
      KONDO Yutaka
    • 依托单位:
    Epigenetic plasticity as a novel target for cancer treatment
    • 批准号:
      22300344
    • 项目类别:
      Grant-in-Aid for Scientific Research (B)
    • 资助金额:
      $10.15万
    • 财政年份:
      2010
    • 负责人:
      KONDO Yutaka
    • 依托单位:
    Studies of impacts of black carbon aerosol on climate based on aircraft observations
    • 批准号:
      19101001
    • 项目类别:
      Grant-in-Aid for Scientific Research (S)
    • 资助金额:
      $70.8万
    • 财政年份:
      2007
    • 负责人:
      KONDO Yutaka
    • 依托单位:
    海外基金