The mechanisms of sexual reproduction of malaria parasites
The mechanisms of sexual reproduction of malaria parasites
批准号:
20590426
负责人:
HIRAI Makoto
金额:
$2.25万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010
中文摘要
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英文摘要
By performing comparative genomics analysis, we identified the malaria orthologue of plant reproduction factor, GCS1 (Generative Cell Specific 1) and named it as PbGCS1. PbGCS1(-) parasites completely lost the fertility, indicating that PbGCS1 is surely functional orthologue of plant GCS1. Our findings indicate that GCS1-based sexual reproduction systems are conserved in various organisms.
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DOI:
10.1128/jcm.00331-10
发表时间:
2010-07-01
期刊:
JOURNAL OF CLINICAL MICROBIOLOGY
影响因子:
9.4
作者:
[Iseki, Hiroshi, Kawai, Satoru, Igarashi, Ikuo]
通讯作者:
Igarashi, Ikuo
Male fertility of malaria parasite is determined by GCS, a plant-typereproduction factor
疟疾寄生虫的雄性生育能力由 GCS(一种植物型繁殖因子)决定
DOI:
--
发表时间:
2008
期刊:
Current Biology 18
影响因子:
--
作者:
[Chang H, Yoshimoto M, Umeda K, Iwasa T, Mizuno Y, Fukada SI, Yamamoto H, Motohashi N, Miyagoe-Suzuki Y, Takeda S, Heike T, Nakahata T, 宮田健, 平井誠]
通讯作者:
平井誠
DOI:
10.1016/j.cub.2008.03.045
发表时间:
2008-04-22
期刊:
CURRENT BIOLOGY
影响因子:
9.2
作者:
[Hirai, Makoto, Arai, Meiji, Matsuoka, Hiroyuki]
通讯作者:
Matsuoka, Hiroyuki
The Plasmodium HU homolog, which binds the plastid DNA sequence-independently, is essential for the parasite's survival
疟原虫 HU 同源物独立地结合质体 DNA 序列,对于寄生虫的生存至关重要
DOI:
--
发表时间:
2009
期刊:
FEBS Letters 583
影响因子:
--
作者:
[Sasaki N, Hirai M, et al]
通讯作者:
et al
マラリア原虫オオシストスポロゾイト形成に必要なプロテアーゼ
疟疾寄生虫卵囊子孢子形成所需的蛋白酶
DOI:
--
发表时间:
2008
期刊:
影响因子:
--
作者:
[平井誠, 川合覚, 新井明治, 松岡裕之]
通讯作者:
松岡裕之
共 23 条
Method for mutation in organelle genome by CRISPR/CAS9
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批准号:15K08453
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.24万
-
财政年份:2015
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负责人:HIRAI Makoto
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依托单位:
Mechanism analyses of development of cardiovascular lesions in long-time workers by multi-biomarkers.
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批准号:22590582
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$3.08万
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财政年份:2010
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负责人:HIRAI Makoto
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依托单位:
Relationship between the care burden, sleep pattern and the circulation function in family caregivers of patients with dementia. And development of health support.
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批准号:19592563
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.91万
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财政年份:2007
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负责人:HIRAI Makoto
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依托单位:
Research on Establishment of Supporting System for In-Home Cardiovascular Medicine
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批准号:15500339
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项目类别:Grant-in-Aid for Scientific Research (C)
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资助金额:$2.05万
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财政年份:2003
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负责人:HIRAI Makoto
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依托单位:
Identification of the amino acid residues of the platelet GPIbα essential for the von Willebrand factor binding by the clustered charged-to-alanine scanning mutagenesis
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批准号:12670659
-
项目类别:Grant-in-Aid for Scientific Research (C)
-
资助金额:$2.11万
-
财政年份:2000
-
负责人:HIRAI Makoto
-
依托单位:
海外基金