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Novel method of measuring activities of enzymes involved in lipid metabolism

Novel method of measuring activities of enzymes involved in lipid metabolism
测量参与脂质代谢的酶活性的新方法
批准号:
20590560
负责人:
KOBAYASHI Junji
金额:
$3.08万
依托单位:
依托单位国家:
日本
项目类别:
Grant-in-Aid for Scientific Research (C)
财政年份:
2008
资助国家:
日本
项目状态:
已结题
起止时间:
2008 至 2010

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中文摘要
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英文摘要
We have established a simple and reliable system for measuring LPL and HTGL activities in post-heparin plasma and investigated clinical significance of measuring those activities. LPL activities showed inverse relations with TG, RLP-TG and sdLDL and positive relations with HDL-C but had no relation with ANGPTL3. HTGL activities showed no relation with TG, RLP-TG and sdLDL but had inverse relations with HDL-C and ANGPTL3. In vitro experiment showed that ANGPTL3 did not inhibit HTGL activities at all, suggesting unidentified molecule may regulate ANGPTL3 and HTGL each other in opposite directions.
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肝性リパーゼ脂質検査アップデート
肝脂肪酶血脂检测更新
DOI: --
发表时间: 2009
期刊: Medical Technology 37巻
影响因子: --
作者: [小林淳二, 今村茂行, 酒瀬川信一, 野口徹, 野原淳, 馬渕宏]
通讯作者: 馬渕宏
Postprandial triglyceridemia in men with impaired fating glucose, impaired glucose tolerance and diabetes.
血糖受损、糖耐量受损和糖尿病男性的餐后甘油三酯血症。
DOI: --
发表时间: 2008
期刊: Diabet Med 25
影响因子: --
作者: [Oka, R., Kobayashi J.]
通讯作者: Kobayashi J.
脂質異常者における肝性リパーゼと血清脂質との関係
血脂异常患者肝脂肪酶与血脂的关系
DOI: --
发表时间: 2009
期刊:
影响因子: --
作者: [小林淳二, 今村茂行, 大家理恵, 野原淳, 川尻剛照、馬渕宏]
通讯作者: 川尻剛照、馬渕宏
DOI: --
发表时间: 2010
期刊: Medical Practice 27巻
影响因子: --
作者: [稲津明広, 小林淳二]
通讯作者: 小林淳二
30
    Elucidation of lipid metabolizing enzyme dynamics as a predictor of cardiovascular events
    • 批准号:
      15K08627
    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $3.08万
    • 财政年份:
      2015
    • 负责人:
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    • 依托单位:
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    • 批准号:
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    • 项目类别:
      Grant-in-Aid for Scientific Research (C)
    • 资助金额:
      $2.08万
    • 财政年份:
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    • 批准号:
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    • 项目类别:
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    • 资助金额:
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    • 财政年份:
      2010
    • 负责人:
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    • 依托单位:
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