EFFECTS OF XENICAL ON LPL AND HTGL FOLLOWING A FAT RICH BREAKFAST
EFFECTS OF XENICAL ON LPL AND HTGL FOLLOWING A FAT RICH BREAKFAST
批准号:
5218197
负责人:
Robert H Eckel
金额:
$0.0万
依托单位:
--
依托单位国家:
美国
项目类别:
财政年份:
--
资助国家:
美国
项目状态:
未结题
起止时间:
至
中文摘要
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英文摘要
Lipoprotein lipase (LPL) and hepatic triglyceride lipase (HTGL) are
enzymes located on the surface of capillary endothelia. These two lipases
act to remove triglyceride from the ore of circulating lipoprotein
particles to initiate remodeling into smaller, denser forms. Xenical is
a drug which, taken orally, inhibits gastric and pancreatic lipase
activity by binding irreversibly to these enzymes to decrease intestinal
fat absorption. Xenical may inhibit systemic lipases such as LPL and HTGL
as well as gastrointestinal lipases. This study will investigate the
effect of xenical and/or its metabolites on plasma LPL and HTGL
activities in the fasted state and during the postprandial period.
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2018 Kern Lipid Conference
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批准号:9610114
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项目类别:
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资助金额:$1.95万
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财政年份:2018
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负责人:Robert H Eckel
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依托单位:
2017 Kern Lipid Conference
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批准号:9396189
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项目类别:
-
资助金额:$1.0万
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财政年份:2017
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负责人:Robert H Eckel
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依托单位:
2015 Kern Lipid Conference
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批准号:8985457
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项目类别:
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资助金额:$1.0万
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财政年份:2015
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负责人:Robert H Eckel
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依托单位:
Obesity and Cardiovascular Disease: Opportunity for Post-Doctoral Training
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批准号:9293351
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项目类别:
-
资助金额:$27.8万
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财政年份:2014
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负责人:Robert H Eckel
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依托单位:
Obesity and Cardiovascular Disease: Opportunity for Post-Doctoral Training
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批准号:8845604
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项目类别:
-
资助金额:$27.23万
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财政年份:2014
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负责人:Robert H Eckel
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依托单位:
Obesity and Cardiovascular Disease: Opportunity for Post-Doctoral Training
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批准号:9390657
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项目类别:
-
资助金额:$0.55万
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财政年份:2014
-
负责人:Robert H Eckel
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依托单位:
Obesity and Cardiovascular Disease: Opportunity for Post-Doctoral Training
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批准号:9064837
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项目类别:
-
资助金额:$28.07万
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财政年份:2014
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负责人:Robert H Eckel
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依托单位:
2012 Kern Lipid Conference
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批准号:8399490
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项目类别:
-
资助金额:$1.5万
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财政年份:2012
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负责人:Robert H Eckel
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依托单位:
Mechanisms of Obesity in Mice with Neuron-Specific Lipoprotein Lipase Deficiency
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批准号:8280420
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项目类别:
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资助金额:$42.04万
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财政年份:2011
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负责人:Robert H Eckel
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依托单位:
Mechanisms of Obesity in Mice with Neuron-Specific Lipoprotein Lipase Deficiency
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批准号:8668938
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项目类别:
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资助金额:$43.31万
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财政年份:2011
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负责人:Robert H Eckel
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依托单位:
Mechanisms of Obesity in Mice with Neuron-Specific Lipoprotein Lipase Deficiency
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批准号:8459513
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项目类别:
-
资助金额:$41.63万
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财政年份:2011
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负责人:Robert H Eckel
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依托单位:
Mechanisms of Obesity in Mice with Neuron-Specific Lipoprotein Lipase Deficiency
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批准号:8106707
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项目类别:
-
资助金额:$49.12万
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财政年份:2011
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负责人:Robert H Eckel
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依托单位:
2010 Kern Aspen Lipid Conference
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批准号:8006954
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项目类别:
-
资助金额:$1.5万
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财政年份:2010
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负责人:Robert H Eckel
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依托单位:
2009 Kern Aspen Lipid Conference
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批准号:7753479
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项目类别:
-
资助金额:$1.25万
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财政年份:2009
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负责人:Robert H Eckel
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依托单位:
2008 Kern Aspen Lipid Conference
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批准号:7541321
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项目类别:
-
资助金额:$1.5万
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财政年份:2008
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负责人:Robert H Eckel
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依托单位:
MECHANISMS DEFENDING FAT MASS IN HUMANS AFTER LIPECTOMY
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批准号:7719427
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项目类别:
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资助金额:$1.2万
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财政年份:2008
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负责人:Robert H Eckel
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依托单位:
MECHANISMS DEFENDING FAT MASS IN HUMANS AFTER LIPECTOMY
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批准号:7604377
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项目类别:
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资助金额:$10.2万
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财政年份:2007
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负责人:Robert H Eckel
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依托单位:
ASSESS CHANGES IN MEMBRANE LIPID COMPOSITION ON A HIGH PROTEIN, LOW CARB DIET
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批准号:7377802
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项目类别:
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资助金额:$2.57万
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财政年份:2006
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负责人:Robert H Eckel
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依托单位:
ASSESS CARDIOVASCULAR RISK ON A HIGH PROTEIN, LOW CARB DIET COMP W/USDA DIET
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批准号:7377801
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项目类别:
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资助金额:$2.51万
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财政年份:2006
-
负责人:Robert H Eckel
-
依托单位:
MECHANISMS DEFENDING FAT MASS IN HUMANS AFTER LIPECTOMY
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批准号:7377776
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项目类别:
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资助金额:$7.86万
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财政年份:2006
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负责人:Robert H Eckel
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依托单位:
海外基金