Establishment of aspiration biopsy-nucleic acid diagnosis detecting IgH monoclonality in malignant lymphoma

恶性淋巴瘤抽吸活检-IgH单克隆核酸诊断的建立

• 批准号: 20590570
• 负责人: TAKANO Toru
• 金额: $ 3.08万
• 依托单位: Osaka University
• 依托单位国家: 日本
• 项目类别: Grant-in-Aid for Scientific Research (C)
• 财政年份: 2008
• 资助国家: 日本
• 起止时间: 2008 至 2010
• 项目状态: 已结题
• 来源: https://kaken.nii.ac.jp/grant/KAKENHI-PROJECT-20590570/
• 关键词: 悪性遺リンパ腫; 甲状腺; IgH遺伝子; モノクロナリティー; 穿刺吸引細胞診; 悪性リンパ腫

VR was performed in patients suspected having thyroid malignant lymphoma. 0 of 2 and 7 of 11 patients of Hashimoto's and malignant lymphoma, respectively, showed a positive result in monoclonality in the IgH gene. A single tube VR method, which requires only a microcentrifuge machine and thermal cycler, was established.

VR 对怀疑患有甲状腺恶性淋巴瘤的患者进行。桥本氏病和恶性淋巴瘤的11名患者中分别有0名和7名患者的IgH基因单克隆性呈阳性。建立了仅需要微量离心机和热循环仪的单管 VR 方法。

项目成果

Arteriosclerosis obliterans associated with anti-cardiolipin antibody/beta2-glycoprotein I antibodies as a strong risk factor for ischaemic heart disease in patients with systemic lupus erythematosus.

与抗心磷脂抗体/β2-糖蛋白 I 抗体相关的动脉硬化闭塞症是系统性红斑狼疮患者缺血性心脏病的强危险因素。

• 发表时间: 2008
• 期刊: Rheumatology (Oxford) 47
• 作者: Nojima;J.;Masuda;Y.;Iwatani;Y.;Kuratsune;H.;Watanabe;Y.;Suehisa;E.;Takano;T.;Hidaka;Y.;Kanakura;Y.
• 通讯作者: Y.

甲状腺腫瘍マーカーおよび甲状腺腫瘍の分子分類法

甲状腺肿瘤标志物及甲状腺肿瘤的分子分类

• 发表时间: 2009

Expression of nestin mRNA is a differentiation marker in thyroid tumors.

• DOI: 10.1016/j.canlet.2009.02.006
• 发表时间: 2009-07
• 期刊: Cancer letters
• 影响因子: 9.7
• 作者: Hiroya Yamada;T. Takano;Yasuhiro Ito;F. Matsuzuka;A. Miya;Kaoru Kobayashi;H. Yoshida;Mikio Watanabe;Y. Iwatani;A. Miyauchi

Outpatient administration of radioactive iodine after total thyroidectomy for pediatric thyroid cancer : A report of three cases.

小儿甲状腺癌甲状腺全切除术后门诊放射性碘治疗：三例报告。

• 发表时间: 2009
• 期刊: Int J Pediatr Otorhi 73(12)
• 作者: Takano T;Yane K;Oue T;Otsuki N;Nibu K;Hidaka Y.
• 通讯作者: Hidaka Y.

Increased expression levels of tensin3 mRNA in thyroid functional adenomas as compared to non-functioning adenomas.

与无功能腺瘤相比，甲状腺功能性腺瘤中张力蛋白 3 mRNA 的表达水平增加。

• 发表时间: 2009
• 期刊: Exp Clin Endocr Diab 117
• 作者: Maeda I;Yamada H;Takano T;Nishihara E;Ito Y;Matsuzuka F;Miya A;Kobayashi K;Yoshida H;Miyauchi A;Hidaka Y.
• 通讯作者: Hidaka Y.