Chemokines in Aqueous humour before and after IntravitrealTriamcinolone Acetonide in Eyes with Macular Edema Associated with Branch Retinal VeinOcclusion

我们对伴有视网膜分支静脉闭塞（ME-BRVO）的黄斑水肿患者玻璃体内注射曲安纳德（IVTA）前后的房水趋化因子水平进行了测定。在基线时，在水中检测到MCP-1和MIP-1a，并且MIP-1b在患有ME-BRVO的眼睛中显著高于对照组。IVTA后1周，大鼠中央凹厚度（FT）显著降低，MCP-1、MIP-1b水平也显著降低。FT的降低仅与MIP-1b的降低相关。这表明类固醇依赖性ME-BRVO与MIP-1b水平密切相关。

We determined the aqueous humour levels of chemokines before and after an intravitreal injection of triamcinolone acetonide (IVTA) in eyes with macular edema associated with a branch retinal vein occlusion (ME-BRVO). At the baseline, MCP-1 and MIP-1a were detected in the aqueous, and MIP-1b was significantly higher in eyes with a ME-BRVO than in controls. One week after IVTA, the foveal thickness (FT) was significantly decreased, and the levels of MCP-1 and MIP-1b were also significantly reduced. The decrease in the FT was correlated with the decrease of only MIP-1b. This indicates that the steroid-dependent ME-BRVO was closely related with the level of MIP-1b.